N-cyclohexyl-4-methylpiperidine-1-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: N-cyclohexyl-4-methylpiperidine-1-carboxamide
• 化学式: C₁₃H₂₄N₂O
• mdl: MFCD03377229
• 分子量: 224.34
• InChiKey: BOSHLBWKQSSSGD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.923
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS
  申请人：Applied Research Systems ARS Holding N.V.

  公开号：EP1732534A1

  公开（公告）日：2006-12-20
• [EN] USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS<br/>[FR] UTILISANT DE DERIVES DE METHYLENE AMIDE EN CAS DE TROUBLES CARDIO-VASCULAIRES
  申请人：APLLIED RES SYSTEMS ARS HOLDIN

  公开号：WO2005082347A1

  公开（公告）日：2005-09-09

  The present invention is related to the use of substituted methylene amide derivatives of Formula (I) for the treatment and/or prevention of cardiovascular disorders such as coronary obstruction and heart failure. In particular, the present invention is related to the use of substituted methylene amide derivatives of Formula (I) in particular for the treatment and/or prevention of endothelial dysfunction in heart failure.