Trimethyl-[2-[2-[2-(trimethylazaniumyl)ethylsulfonyl]ethylsulfonyl]ethyl]azanium

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 英文名称: Trimethyl-[2-[2-[2-(trimethylazaniumyl)ethylsulfonyl]ethylsulfonyl]ethyl]azanium
• 化学式: C12H30N2O4S2+2
• 分子量: 330.5
• InChiKey: AYMDVQYYVPAZLO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  85
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• COMPOSITIONS COMPRISING COPPER CHELATORS AND METHODS OF USE THEREOF FOR TREATING VASCULOPATHIES
  申请人：INSMED INCORPORATED

  公开号：US20190231815A1

  公开（公告）日：2019-08-01

  The present invention relates to copper chelator compounds and their use for treating vasculopathies, for example, pulmonary hypertension (e.g., pulmonary arterial hypertension or portopulmonary hypertension). The methods include administering a composition comprising an effective amount of a copper chelator compound to a patient in need thereof. Administration can be via oral, intraperitoneal, transdermal, intravenous and inhalation routes. In another aspect of the invention, compositions are provided comprising a copper chelator compound complexed to or encapsulated by a lipid component, for example, a copper chelator encapsulated by a liposome and methods of treatment employing the same.
• US7189865B2
  申请人：——

  公开号：US7189865B2

  公开（公告）日：2007-03-13
• US7851505B2
  申请人：——

  公开号：US7851505B2

  公开（公告）日：2010-12-14