2-[2-(4-piperidin-1-ylphenyl)vinyl]quinoxaline | 1370616-79-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 2-[2-(4-piperidin-1-ylphenyl)vinyl]quinoxaline
• 英文别名: 2-[(E)-2-(4-piperidin-1-ylphenyl)ethenyl]quinoxaline
• CAS: 1370616-79-7
• 化学式: C₂₁H₂₁N₃
• 分子量: 315.418
• InChiKey: LCJOKXCDXNBVGB-DHZHZOJOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  29
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-甲基喹喔啉 、 4-哌啶-1-基-苯甲醛 在 甲基三辛基氯化铵 、 sodium hydroxide 作用下， 以 水 为溶剂， 反应 15.0h， 以42%的产率得到2-[2-(4-piperidin-1-ylphenyl)vinyl]quinoxaline
  参考文献：
  名称：

  Synthesis and Photophysical Investigation of a Series of Push–Pull Arylvinyldiazine Chromophores

  摘要：

  A new series of push-pull arylvinyldiazines has been efficiently prepared by aldol condensation between the appropriate methyldiazine and aromatic aldehyde. The optical absorption and emission properties of these chromophores were studied in different solvents and media. These compounds act as polarity sensors with a strong positive emission solvatochromism. This behavior suggests a highly polar emitting state, which is characteristic of compounds that undergo an internal charge transfer upon excitation. These molecules also exhibit halochromic properties and are potential colorimetric and luminescence pH sensors. The second-order nonlinear properties have been investigated for some of the compounds, and large and positive mu beta are obtained, in particular, for pyrimidine derivatives.

  DOI：

  10.1021/jo3004919

文献信息

• Synthesis and Photophysical Investigation of a Series of Push–Pull Arylvinyldiazine Chromophores
  作者：Sylvain Achelle、Alberto Barsella、Christine Baudequin、Bertrand Caro、Françoise Robin-le Guen

  DOI：10.1021/jo3004919

  日期：2012.4.20

  A new series of push-pull arylvinyldiazines has been efficiently prepared by aldol condensation between the appropriate methyldiazine and aromatic aldehyde. The optical absorption and emission properties of these chromophores were studied in different solvents and media. These compounds act as polarity sensors with a strong positive emission solvatochromism. This behavior suggests a highly polar emitting state, which is characteristic of compounds that undergo an internal charge transfer upon excitation. These molecules also exhibit halochromic properties and are potential colorimetric and luminescence pH sensors. The second-order nonlinear properties have been investigated for some of the compounds, and large and positive mu beta are obtained, in particular, for pyrimidine derivatives.