(3R)-N-(2,2-dimethylpropyl)piperidin-3-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: (3R)-N-(2,2-dimethylpropyl)piperidin-3-amine
• 化学式: C₁₀H₂₂N₂
• 分子量: 170.3
• InChiKey: HSXSSCUJZUJQRI-SECBINFHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• COMPOUNDS AND COMPOSITIONS FOR IRE1 INHIBITION
  申请人：Optikira LLC

  公开号：US20200354367A1

  公开（公告）日：2020-11-12

  The present invention provides novel compounds, compositions and methods for treating or preventing an IRE1α-related disease or disorder. In certain embodiments, the disease or disorder is selected from the group consisting of a neurodegenerative disease, a demyelinating disease, cancer, an eye disease, a fibrotic disease, and diabetes.
• Imidazolopyridine Compounds For IRE1 Inhibition
  申请人：Optikira, LLC

  公开号：US20220194945A1

  公开（公告）日：2022-06-23

  The present invention provides novel imidazolopyrazine compounds, compositions and methods for treating or preventing an IRE1α-related disease or disorder. In certain embodiments, the disease or disorder is selected from the group consisting of a neurodegenerative disease, a demyelinating disease, cancer, an eye disease, a fibrotic disease, and diabetes.