thiocyanuric acid | 32709-46-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: thiocyanuric acid
• 英文别名: Monothiocyanursaeure；6-thioxo-[1,3,5]triazinane-2,4-dione；6-sulfanylidene-1,3,5-triazinane-2,4-dione
• CAS: 32709-46-9
• 化学式: C₃H₃N₃O₂S
• 分子量: 145.142
• InChiKey: LDPJMRXAPFPLQV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  102
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-硝基邻苯二腈 、 thiocyanuric acid 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 48.0h， 以59%的产率得到2,4,6-tris(3-thiopthalonitrile)-s-triazine
  参考文献：
  名称：

  Nanosecond nonlinear optical limiting properties of new trinuclear lanthanide phthalocyanines in solution and as thin films

  摘要：

  2,4,6-Tris[3-thio-9,10,16,17,23,24-hexa(4-tertbutylphenoxy) phthalocyaninato ytterbium (III) chloride]-s-triazin (3) and its lutetium counterpart (4) were synthesized. The nonlinear optical behavior of 3 and 4 were characterized in solution and when embedded in polymer as thin films. Thin films of complexes 3 and 4 in poly(bisphenol A carbonate) showed improved nonlinear optical properties when compared to solution. Complex 3 showed a lower threshold for optical limiting intensity (I-lim) than complex 4, and for phthalocyanines in general. I-lim values were even lower in films compared to solutions. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2014.08.047
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 盐酸 作用下， 生成 thiocyanuric acid
  参考文献：
  名称：

  Diels; Liebermann, Chemische Berichte, 1903, vol. 36, p. 3195

  摘要：

  DOI：

文献信息

• AMINOCARBOXYLIC ACID DERIVATIVE AND MEDICINAL USE THEREOF
  申请人：Habashita Hiromu

  公开号：US20090275554A1

  公开（公告）日：2009-11-05

  The present invention relates to a compound represented by the formula (I), a salt thereof, an N-oxide form thereof, a solvate thereof, or a prodrug thereof, and a medicament containing the same. The compound represented by the formula (I) has an ability to bind to an S1P receptor (particularly, EDG-1, EDG-6, and/or EDG-8) and is useful for preventing and/or treating for rejection to transplantation, graft-versus-host disease, autoimmune diseases, allergic diseases, neurodegenerating diseases, and the like. wherein all symbols are described in the specification.

  本发明涉及一种由公式（I）表示的化合物，其盐，其N-氧化物形式，其溶剂化物或其前药，以及含有该化合物的药物。公式（I）表示的化合物具有结合S1P受体（特别是EDG-1，EDG-6和/或EDG-8）的能力，可用于预防和/或治疗移植排斥，移植物抗宿主病，自身免疫性疾病，过敏性疾病，神经退行性疾病等。其中所有符号在说明书中描述。
• Aminocarboxylic acid derivative and medicinal use thereof
  申请人：Ono Pharmaceutical Co., Ltd.

  公开号：US07906549B2

  公开（公告）日：2011-03-15

  The present invention relates to a compound represented by the formula (I), a salt thereof, an N-oxide form thereof, a solvate thereof, or a prodrug thereof, and a medicament containing the same. The compound represented by the formula (I) has an ability to bind to an S1P receptor (particularly, EDG-1, EDG-6, and/or EDG-8) and is useful for preventing and/or treating for rejection to transplantation, graft-versus-host disease, autoimmune diseases, allergic diseases, neurodegenerating diseases, and the like. wherein all symbols are described in the specification.

  本发明涉及一个由公式（I）表示的化合物，其盐，N-氧化物形式，溶剂合物或前药，以及含有该化合物的药物。由公式（I）表示的化合物具有结合S1P受体（特别是EDG-1，EDG-6和/或EDG-8）的能力，并可用于预防和/或治疗移植排斥反应，移植物抗宿主病，自身免疫性疾病，过敏性疾病，神经退行性疾病等。其中所有符号均在说明书中描述。
• GORDETSOV, A. S.;KOZINA, A. P.;SKOBELEVA, S. E.;MUSHKIN, YU. I.;ZAXAROVA,+, METALLOORGAN. XIMIYA, 2,(1989) N, S. 1129-1135
  作者：GORDETSOV, A. S.、KOZINA, A. P.、SKOBELEVA, S. E.、MUSHKIN, YU. I.、ZAXAROVA,+

  DOI：——

  日期：——
• Nanosecond nonlinear optical limiting properties of new trinuclear lanthanide phthalocyanines in solution and as thin films
  作者：Kutloano E. Sekhosana、Edith Amuhaya、Tebello Nyokong

  DOI：10.1016/j.poly.2014.08.047

  日期：2015.1

  2,4,6-Tris[3-thio-9,10,16,17,23,24-hexa(4-tertbutylphenoxy) phthalocyaninato ytterbium (III) chloride]-s-triazin (3) and its lutetium counterpart (4) were synthesized. The nonlinear optical behavior of 3 and 4 were characterized in solution and when embedded in polymer as thin films. Thin films of complexes 3 and 4 in poly(bisphenol A carbonate) showed improved nonlinear optical properties when compared to solution. Complex 3 showed a lower threshold for optical limiting intensity (I-lim) than complex 4, and for phthalocyanines in general. I-lim values were even lower in films compared to solutions. (C) 2014 Elsevier Ltd. All rights reserved.
• Diels; Liebermann, Chemische Berichte, 1903, vol. 36, p. 3195
  作者：Diels、Liebermann

  DOI：——

  日期：——