摩熵化学
数据库官网
小程序
打开微信扫一扫
首页 分子通 化学资讯 化学百科 反应查询 关于我们
请输入关键词
历史搜索
    热门化合物HOT
    • 喹啉
    • 水杨醛
    • 二溴甲烷
    • 谷胱甘肽
    • L-乳酸
    • 苯巴比妥
    • 辣椒碱
    • 非那明
    • 百草枯
    • 联苯烯
    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 二嗪类

    二嗪类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— N-[4-[(1R,3R,4R,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-methylsulfonylphenyl)imidazo[1,5-b]pyridazin-7-amine —— C26H28F2N6O3S
    N-[4-[(1R,3R,4R,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-methylsulfonylphenyl)imidazo[1,5-b]pyridazin-7-amine
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxolan-3-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C30H34F2N8O4
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxolan-3-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— N-[4-[(1R,3R,4S,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-methylphenyl)imidazo[1,5-b]pyridazin-7-amine —— C26H28F2N6O
    N-[4-[(1R,3R,4S,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-methylphenyl)imidazo[1,5-b]pyridazin-7-amine
    —— 1-[[4-[7-[[4-[(3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]methyl]pyrrolidin-2-one —— C28H30F2N8O2
    1-[[4-[7-[[4-[(3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]methyl]pyrrolidin-2-one
    —— N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(4-fluorooxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylacetamide —— C32H36F3N7O2
    N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(4-fluorooxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylacetamide
    —— N-[4-[(1R,3R,4S,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(methoxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-amine —— C27H30F2N6O2
    N-[4-[(1R,3R,4S,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(methoxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-amine
    —— 1-[[4-[7-[[4-[(3R,4S,5S)-3-amino-5-methyl-4-(2-methylsulfonylethoxy)piperidin-1-yl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]methyl]pyrrolidin-2-one —— C31H36F2N8O4S
    1-[[4-[7-[[4-[(3R,4S,5S)-3-amino-5-methyl-4-(2-methylsulfonylethoxy)piperidin-1-yl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]methyl]pyrrolidin-2-one
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-methoxyphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C27H30F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-(2,6-difluoro-4-methoxyphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylacetamide —— C33H39F2N7O3
    N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylacetamide
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C30H34F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— (3R,4R,5S)-3-amino-1-[3-[[2-[4-(ethoxymethyl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-ol —— C26H29F2N7O2
    (3R,4R,5S)-3-amino-1-[3-[[2-[4-(ethoxymethyl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-ol
    —— 3-[4-[7-[[4-[(1R,3R,4S,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxetan-3-ol —— C28H30F2N6O4S
    3-[4-[7-[[4-[(1R,3R,4S,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxetan-3-ol
    —— N-[4-[(1R,3R,4S,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxolan-3-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-amine —— C29H32F2N6O3
    N-[4-[(1R,3R,4S,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxolan-3-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-amine
    —— 3-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(3-hydroxyoxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]oxypropanenitrile —— C29H30F2N8O3
    3-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(3-hydroxyoxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]oxypropanenitrile
    —— N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylacetamide —— C32H37F2N7O3
    N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(oxan-4-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylacetamide
    —— 3-[4-[7-[[4-[(1R,3R,4R,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxetan-3-ol —— C28H30F2N6O4S
    3-[4-[7-[[4-[(1R,3R,4R,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxetan-3-ol
    —— N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(4-fluorooxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]acetamide —— C30H33F3N8O2
    N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(4-fluorooxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]acetamide
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-hydroxyethoxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C27H30F2N8O4
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-hydroxyethoxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— 2-[4-[7-[[4-[(1R,3S)-3-aminocyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]ethanol —— C25H26F2N6O
    2-[4-[7-[[4-[(1R,3S)-3-aminocyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]ethanol
    —— 4-[4-[7-[[4-[(1R,3R,4S,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxane-4-carbonitrile —— C31H33F2N7O2
    4-[4-[7-[[4-[(1R,3R,4S,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxane-4-carbonitrile
    —— (3R,4R,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(3-methoxyoxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-ol —— C27H29F2N7O3
    (3R,4R,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(3-methoxyoxetan-3-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-ol
    —— N-[4-[(1R,3R,4R,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-methylsulfonylphenyl)imidazo[1,5-b]pyridazin-7-amine —— C26H28F2N6O4S2
    N-[4-[(1R,3R,4R,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-methylsulfonylphenyl)imidazo[1,5-b]pyridazin-7-amine
    —— 3-[7-[[4-[(1R,3S)-3-aminocyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-2,4-difluoro-N-propan-2-ylbenzamide —— C27H29F2N7O
    3-[7-[[4-[(1R,3S)-3-aminocyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-2,4-difluoro-N-propan-2-ylbenzamide
    —— 3-[7-[[4-[(1R,3R,4S,5S)-3-amino-4-(2-cyanoethoxy)-5-methylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-2,4-difluoro-N-propan-2-ylbenzamide —— C31H34F2N8O2
    3-[7-[[4-[(1R,3R,4S,5S)-3-amino-4-(2-cyanoethoxy)-5-methylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-2,4-difluoro-N-propan-2-ylbenzamide
    —— N-[4-[(1R,3S)-3-aminocyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-amine —— C28H30F2N6O2
    N-[4-[(1R,3S)-3-aminocyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-amine
    —— N-[4-[(1R,3R,4S,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-methylphenyl)imidazo[1,5-b]pyridazin-7-amine —— C26H28F2N6O2S
    N-[4-[(1R,3R,4S,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-methylphenyl)imidazo[1,5-b]pyridazin-7-amine
    —— 3-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxolan-3-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]oxypropanenitrile —— C30H32F2N8O3
    3-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(oxolan-3-yloxy)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]oxypropanenitrile
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[4-(4-cyanooxan-4-yl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate —— C31H33F2N9O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[4-(4-cyanooxan-4-yl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]carbamate
    —— 3-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(1-fluorocyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]oxypropanenitrile —— C31H33F3N8O
    3-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(1-fluorocyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]oxypropanenitrile
    —— 3-[4-[7-[[4-[(1R,3R,4R,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxetan-3-ol —— C28H30F2N6O3
    3-[4-[7-[[4-[(1R,3R,4R,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxetan-3-ol
    —— N-[4-[(1R,3R,4S,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-amine —— C31H36F2N6O4S
    N-[4-[(1R,3R,4S,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-amine
    —— 3-[7-[[4-[(1R,3R,4R,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-2,4-difluoro-N-propan-2-ylbenzamide —— C29H33F2N7O2
    3-[7-[[4-[(1R,3R,4R,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-2,4-difluoro-N-propan-2-ylbenzamide
    —— N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-hydroxyethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]acetamide —— C27H30F2N8O2
    N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(2-hydroxyethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]acetamide
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-3-(propan-2-ylcarbamoyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate —— C30H34F2N8O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-3-(propan-2-ylcarbamoyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate
    —— N-[4-[(3R,4S,5S)-3-amino-5-methyl-4-(2-methylsulfonylethoxy)piperidin-1-yl]pyridin-3-yl]-2-[4-(ethoxymethyl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-amine —— C29H35F2N7O4S
    N-[4-[(3R,4S,5S)-3-amino-5-methyl-4-(2-methylsulfonylethoxy)piperidin-1-yl]pyridin-3-yl]-2-[4-(ethoxymethyl)-2,6-difluorophenyl]imidazo[1,5-b]pyridazin-7-amine
    —— N-[4-[(1R,3R,4R,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-amine —— C30H34F2N6O2
    N-[4-[(1R,3R,4R,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-amine
    —— N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-propan-2-yloxyphenyl)imidazo[1,5-b]pyridazin-7-amine —— C27H30F2N6O
    N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-propan-2-yloxyphenyl)imidazo[1,5-b]pyridazin-7-amine
    —— N-[4-[(3R,4S,5S)-3-amino-5-methyl-4-(2-methylsulfonylethoxy)piperidin-1-yl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-amine —— C32H39F2N7O5S
    N-[4-[(3R,4S,5S)-3-amino-5-methyl-4-(2-methylsulfonylethoxy)piperidin-1-yl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-amine
    —— N-[4-[(3S,5R)-3-amino-5-methylpiperidin-1-yl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-amine —— C29H33F2N7O2
    N-[4-[(3S,5R)-3-amino-5-methylpiperidin-1-yl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-amine
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-[(2-oxopyrrolidin-1-yl)methyl]phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate —— C31H34F2N8O3
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-[(2-oxopyrrolidin-1-yl)methyl]phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]carbamate
    —— N-[4-[(1R,3R,4R,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-propan-2-yloxyphenyl)imidazo[1,5-b]pyridazin-7-amine —— C28H32F2N6O3S
    N-[4-[(1R,3R,4R,5S)-3-amino-5-methyl-4-methylsulfonylcyclohexyl]pyridin-3-yl]-2-(2,6-difluoro-4-propan-2-yloxyphenyl)imidazo[1,5-b]pyridazin-7-amine
    —— N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(methoxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]acetamide —— C27H30F2N8O2
    N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(methoxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]acetamide
    —— 3-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(2-hydroxyethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]oxypropanenitrile —— C29H31F2N7O2
    3-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-[2,6-difluoro-4-(2-hydroxyethyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]oxypropanenitrile
    —— N-[4-[(1R,3R,4R,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-amine —— C31H36F2N6O3
    N-[4-[(1R,3R,4R,5S)-3-amino-4-methoxy-5-methylcyclohexyl]pyridin-3-yl]-2-[2,6-difluoro-4-(oxan-4-yloxymethyl)phenyl]imidazo[1,5-b]pyridazin-7-amine
    —— methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(1-methoxycyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate —— C32H38F2N8O3
    methyl N-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(1-methoxycyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]-N-methylcarbamate
    —— 4-[4-[7-[[4-[(1R,3R,4S,5S)-3-amino-5-methyl-4-(2-methylsulfonylethoxy)cyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxan-4-ol —— C32H38F2N6O5S
    4-[4-[7-[[4-[(1R,3R,4S,5S)-3-amino-5-methyl-4-(2-methylsulfonylethoxy)cyclohexyl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxan-4-ol
    —— methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-(2,6-difluoro-4-methylsulfonylphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate —— C28H31F2N7O4S
    methyl N-[(1S,2R,4R,6S)-2-amino-4-[3-[[2-(2,6-difluoro-4-methylsulfonylphenyl)imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-6-methylcyclohexyl]-N-methylcarbamate
    —— N-[4-[(3R,4S,5S)-3-amino-5-methyl-4-(2-methylsulfonylethoxy)piperidin-1-yl]pyridin-3-yl]-2-[2,6-difluoro-4-(1-fluorocyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-amine —— C31H36F3N7O3S
    N-[4-[(3R,4S,5S)-3-amino-5-methyl-4-(2-methylsulfonylethoxy)piperidin-1-yl]pyridin-3-yl]-2-[2,6-difluoro-4-(1-fluorocyclopentyl)phenyl]imidazo[1,5-b]pyridazin-7-amine
    —— 4-[4-[7-[[4-[(3S,5R)-3-amino-5-methylpiperidin-1-yl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxan-4-ol —— C28H31F2N7O2
    4-[4-[7-[[4-[(3S,5R)-3-amino-5-methylpiperidin-1-yl]pyridin-3-yl]amino]imidazo[1,5-b]pyridazin-2-yl]-3,5-difluorophenyl]oxan-4-ol
    —— 3-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(4-fluorooxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]oxypropanenitrile —— C31H33F3N8O2
    3-[(3R,4S,5S)-3-amino-1-[3-[[2-[2,6-difluoro-4-(4-fluorooxan-4-yl)phenyl]imidazo[1,5-b]pyridazin-7-yl]amino]pyridin-4-yl]-5-methylpiperidin-4-yl]oxypropanenitrile