4-dimethylamino-6-diphenylamino-2-(1H-1-pyrrolyl)-1,3,5-triazine | 633279-22-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 4-dimethylamino-6-diphenylamino-2-(1H-1-pyrrolyl)-1,3,5-triazine
• 英文别名: N,N-dimethyl-N',N'-diphenyl-6-(1H-pyrrol-1-yl)-1,3,5-triazine-2,4-diamine；4-N,4-N-dimethyl-2-N,2-N-diphenyl-6-pyrrol-1-yl-1,3,5-triazine-2,4-diamine
• CAS: 633279-22-8
• 化学式: C₂₁H₂₀N₆
• mdl: MFCD03820535
• 分子量: 356.43
• InChiKey: JCSNVVBAWMCJDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  50.1
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2,5-二甲氧基四氢呋喃 、 2-amino-4-dimethylamino-6-diphenylamino-1,3,5-triazine 在 phosphorus pentoxide 作用下， 以 甲苯 为溶剂， 以73%的产率得到4-dimethylamino-6-diphenylamino-2-(1H-1-pyrrolyl)-1,3,5-triazine
  参考文献：
  名称：

  三嗪类。8. 4,6-二取代的2-（1H-吡咯基）-1,3,5-三嗪的合成及一些反应

  摘要：

  We have studied the reaction of 2,5-dimethoxytetrahydrofuran with 4,6-disubstituted 2-amino-1,3,5-triazines with the aim of obtaining novel coupled polyheterocyclic systems with potential bioactivity. Reaction conditions were optimized. A series of novel 4,6-disubstituted 2-(1H-1-pyrrolyl)-sym-triazines was obtained. It was found that the product yields depended on the nature of the substituent in the 4 and 6 positions of the triazine ring and on the reaction conditions.

  DOI：

  10.1007/s10593-008-0050-4

文献信息

• sym-triazines. 8. Synthesis and some reactions of 4,6-disubstituted 2-(1H-pyrrolyl)-1,3,5-triazines
  作者：A. A. Chesnyuk、S. N. Mikhailichenko、V. N. Zaplishnyi、L. D. Konyushkin、S. I. Firgang

  DOI：10.1007/s10593-008-0050-4

  日期：2008.3

  We have studied the reaction of 2,5-dimethoxytetrahydrofuran with 4,6-disubstituted 2-amino-1,3,5-triazines with the aim of obtaining novel coupled polyheterocyclic systems with potential bioactivity. Reaction conditions were optimized. A series of novel 4,6-disubstituted 2-(1H-1-pyrrolyl)-sym-triazines was obtained. It was found that the product yields depended on the nature of the substituent in the 4 and 6 positions of the triazine ring and on the reaction conditions.