O,O-dipropylhydrazidophosphate | 61922-08-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: O,O-dipropylhydrazidophosphate
• 英文别名: Di-n-propylphosphorohydrazidat；dipropyl phosphorylhydrazide；dipropylphosphorylhydrazine；phosphorohydrazidic acid dipropyl ester；dipropoxyphosphorylhydrazine
• CAS: 61922-08-5
• 化学式: C₆H₁₇N₂O₃P
• 分子量: 196.186
• InChiKey: AFGWYZDCBOZYPI-UHFFFAOYSA-N

物化性质

• 沸点：
  253.2±23.0 °C(Predicted)
• 密度：
  1.108±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.41
• 重原子数：
  12.0
• 可旋转键数：
  7.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  73.58
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  O,O-dipropylhydrazidophosphate 以 乙腈 、 苯 为溶剂， 生成 N'-{4-[(Diisopropoxy-phosphoryl)-hydrazono]-cyclohexa-2,5-dienylidene}-phosphorohydrazidic acid dipropyl ester
  参考文献：
  名称：

  Kutyrev, A. A.; Ovrutskii, D. G.; Moskva, V. V., Journal of general chemistry of the USSR, 1988, vol. 58, # 4, p. 699 - 705

  摘要：

  DOI：
• 作为产物：
  描述：

  亚磷酸酯二正丙脂 在 苄基三乙基氯化铵 、 potassium carbonate 、 一水合肼 作用下， 生成 O,O-dipropylhydrazidophosphate
  参考文献：
  名称：

  Solid-Liquid Phase-Transfer-Catalysed Phosphorylation of Hydrazine. Preparation of Dialkyl Phosphorohydrazidates and N,N′-Bis[dialkoxyphosphoryl]hydrazines

  摘要：

  DOI：

  10.1055/s-1976-25385

文献信息

• An efficient synthesis of O,O- Di Propyl (E)-2-[1-methyl 2-oxopropylidene]phosphorohydrazidothiolate (E) Oxime and Its Analogues: A Potential Marine Toxin
  作者：Arvind K. Gupta、D. K. Dubey、B. D. Parashar、M. P. Kaushik

  DOI：10.1080/10426500701796249

  日期：2008.7.4

  An efficient method for the synthesis of Ptychodiscus brevis toxin O,O- di n-propyl (E)-2-[1-methyl 2-oxopropylidene]phosphorohydrazidothiolate (E) oxime (TG-1) and its analogues has been developed using thermally stable and recyclable silica gel and Na2SO4 as a condensing agent and water scavenger, respectively. The compounds were evaluated against fish Rasbora daniconius by determining the LC50 and LC90 values. The results of biological evaluation showed that these compounds have high degree of toxicity.
• Kutyrev, A. A.; Ovrutskii, D. G.; Moskva, V. V., Journal of general chemistry of the USSR, 1988, vol. 58, # 2, p. 420 - 421
  作者：Kutyrev, A. A.、Ovrutskii, D. G.、Moskva, V. V.

  DOI：——

  日期：——
• An Efficient One-Pot Synthesis of Some New Substituted 1,2,3,5-Thiatriazolidin-4-one 1,1-Dioxides
  作者：Monaem Balti、Khaireddine Dridi、Mohamed Lotfi El Efrit

  DOI：10.3987/com-14-12980

  日期：——

  A series of some new 1,2,3,5-thiatriazolidin-4-one 1,1-dioxides derivatives were synthesized by reacting respectively beta-cyanohydrazines and phosphorylated hydrazine with chlorosulfonyl isocyanate in good yields. The structures of all the newly prepared compounds were confirmed by IR, H-1, C-13, P-31-NMR spectral data and elemental analysis.
• Diastereoselective Synthesis of New Dialkylphosphorylhydrazones
  作者：Janaína Marques Rodrigues、Carlos Mauricio R. Sant’Anna、Victor Marcos Rumjanek、João Batista Neves DaCosta

  DOI：10.1080/10426500903444366

  日期：2009.12.29

  A series of 22 dialkylphosphorylydrazones (dialkyl ester, N'-[(1E)-(R(1) phenyl)methylene]-phosphorohydrazidic acid), 20 of them new, along with three new N,N'-bis(diisobutylphosphorylthioamide)diamines (bis-[diisobutyl ester), N-thioxomethylene]-, diamine)phosphoramidic acid, were prepared and characterized by IR, (1)H NMR, (13)C NMR, (31)P NMR, and mass spectrometry. The analysis of (1)H NMR, (13)C NMR, (31)P NMR, and NOE spectra confirmed the observation of the single diastereoisomer E in the synthesis of dialkylphosphorylydrazones. The results of a molecular modeling study performed in order to investigate the mechanism of the synthesis of dialkylphosphorylydrazones are in agreement with the experimental results, i.e., the favored formation of diastereoisomer E over Z.
• Kutyrev, A. A.; Ovrutskii, D. G.; Konyukhova, N. D., Journal of general chemistry of the USSR, 1989, vol. 59, p. 1358 - 1361
  作者：Kutyrev, A. A.、Ovrutskii, D. G.、Konyukhova, N. D.、Moskva, V. V.

  DOI：——

  日期：——