phosphoric acid dibutyl ester ethyl ester | 7242-58-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: phosphoric acid dibutyl ester ethyl ester
• 英文别名: phosphoric acid ethyl ester-dibutyl ester；Phosphorsaeure-aethylester-dibutylester；Aethyl-dibutyl-phosphat；Di-n-butyl-ethyl-phosphat；Dibutyl-aethyl-phosphat；Ethyl-dibutyl-phosphat；dibutyl ethyl phosphate
• CAS: 7242-58-2
• 化学式: C₁₀H₂₃O₄P
• 分子量: 238.264
• InChiKey: NAIBHQRYLPOHGG-UHFFFAOYSA-N

物化性质

• 沸点：
  95-96 °C(Press: 3-4 Torr)
• 密度：
  1.1200 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  磷酸三乙酯 、 磷酸三丁酯 生成 phosphoric acid dibutyl ester ethyl ester
  参考文献：
  名称：

  Preparation of neutral mixed phosphates by interaction of phosphates

  摘要：

  公开号：

  US02852549A1

文献信息

• ANTIMICROBIAL OXAZOLIDINONE PRODRUGS
  申请人：Macielag Mark J.

  公开号：US20080027053A1

  公开（公告）日：2008-01-31

  This invention includes oxazolidinone prodrug compounds of Formula (I) and Formula (II) as defined herein. The prodrugs are convertible by natural biological processes into an active ingredient possessed of antimicrobial properties useful in treating bacterial infections in mammals.

  这项发明包括本文所定义的Formula (I)和Formula (II)的噁唑烷酮前药化合物。这些前药可以通过自然生物过程转化为一种具有抗微生物特性的活性成分，可用于治疗哺乳动物体内的细菌感染。
• Synthesis of Mixed Trialkyl Phosphates: Oxidative Phosphorylation of Alcohols with Dialkyl Phosphonates in the Presence of Copper(II) Chloride
  作者：Yoshiki Okamoto、Tetuya Kusano、Setsuo Takamuku

  DOI：10.1246/bcsj.61.3359

  日期：1988.9

  Mixed trialkyl phosphates were synthesized by oxidative phosphorylation of alcohols with dialkyl phosphonates and oxygen in the presence of copper(II) chloride in fairly good yields.

  在氯化铜 (II) 存在下，通过醇与膦酸二烷基酯和氧气的氧化磷酸化合成混合磷酸三烷基酯，收率相当好。
• Lubricant Composition for Fluid Dynamic Bearing
  申请人：Okada Tahei

  公开号：US20070281873A1

  公开（公告）日：2007-12-06

  A lubricating oil composition for fluid dynamic bearings which comprises 50 to 100% by mass of an ether compound comprising at least one ether bond and having 11 to 34 carbon atoms as the base oil and has a kinematic viscosity of at least 2.2 mm 2 /s at 100° C. is provided. The composition has excellent viscosity characteristics such as excellent fluidity at low temperatures and a small decrease in the viscosity in a high temperature range, exhibits lower evaporability, excellent energy saving property and excellent heat stability and is advantageously used for compact fluid dynamic bearings used under rotation at a high speed.

  提供一种用于流体动力轴承的润滑油组合物，其包括质量百分比为50至100%的醚化合物作为基础油，该醚化合物至少包含一个醚键，碳原子数为11至34个，并且在100°C时具有至少2.2 mm²/s的运动黏度。该组合物具有出色的黏度特性，如低温下的出色流动性和高温范围内黏度的小幅降低，表现出较低的挥发性，出色的节能性能和优异的热稳定性，适用于在高速旋转下使用的紧凑型流体动力轴承。
• Synthesis of Mixed Alkylphosphites and Alkylphosphates
  作者：Gheorghe Ilia、Adriana Popa、Smaranda Iliescu、Alina Bora、Gheorghe Dehelean、Aurelia Pascariu

  DOI：10.1080/10426500307865

  日期：2003.7

  Some mixed phosphites having two different alkyl chain were obtained as forerunners for mixed phosphates Mixed dialkyl phosphates were obtained in good yields (40-80%) by phase transfer catalysis in liquid-liquid sistem, starting from different dialkyl phosphites and aliphatic alcohols. The reaction conditions were optimized in order to obtain good yields in phosphites and phosphates respectively.

  获得了一些具有两种不同烷基链的混合亚磷酸酯，作为混合磷酸酯的先导。从不同的亚磷酸二烷基酯和脂肪醇开始，在液-液系统中通过相转移催化以良好的收率（40-80%）获得了混合磷酸二烷基酯。优化反应条件以分别获得亚磷酸盐和磷酸盐的良好收率。通过IR、P 31 -NMR分析化合物。
• Prodrugs of Heteraromatic Compounds
  申请人：Alkermes Pharma Ireland Limited

  公开号：US20160009713A1

  公开（公告）日：2016-01-14

  The present invention relates to prodrugs of parent drug compounds containing heteroaromatic NH groups.

  本发明涉及含有杂芳基NH基团的母药化合物的前药。