4-[Chloro(diphenyl)methyl]benzohydrazide

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 4-[Chloro(diphenyl)methyl]benzohydrazide
• 英文别名: 4-[chloro(diphenyl)methyl]benzohydrazide
• 化学式: C₂₀H₁₇ClN₂O
• 分子量: 336.8
• InChiKey: CVSGOHUTVOYBIL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  55.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Solid phase peptide synthesis processes and associated systems
  申请人：Massachusetts Institute of Technology

  公开号：US10889613B2

  公开（公告）日：2021-01-12

  Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.

  一般描述了进行固相肽合成的系统和工艺。 固相多肽合成是一种已知的工艺，在这种工艺中，氨基酸残基被添加到固定在固体支持物上的多肽中。 在某些实施例中，本发明的系统和方法可用于快速进行固相肽合成，同时保持高产率。 某些实施方案涉及的工艺和系统可用于加热、运输和/或混合试剂，从而减少进行固相肽合成所需的时间。
• SOLID PHASE PEPTIDE SYNTHESIS PROCESSES AND ASSOCIATED SYSTEMS
  申请人：Massachusetts Institute of Technology

  公开号：EP2970374A2

  公开（公告）日：2016-01-20
• SOLID PHASE PEPTIDE SYNTHESIS
  申请人：Massachusetts Institute of Technology

  公开号：EP2970374B1

  公开（公告）日：2019-11-06
• US20140275481A1
  申请人：——

  公开号：US20140275481A1

  公开（公告）日：2014-09-18
• SOLID PHASE PEPTIDES SYNTHESIS PROCESSES AND ASSOCIATED SYSTEMS
  申请人：Massachusetts Institute of Technology

  公开号：US20160102118A1

  公开（公告）日：2016-04-14

  Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.