2,4-Diaethyl-6-methyl-s-triazin | 30362-60-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 2,4-Diaethyl-6-methyl-s-triazin
• 英文别名: 2,4-Diethyl-6-methyl-1,3,5-triazin；2,4-diethyl-6-methyl-[1,3,5]triazine；2,4-Diethyl-6-methyl-1,3,5-triazine
• CAS: 30362-60-8
• 化学式: C₈H₁₃N₃
• 分子量: 151.211
• InChiKey: GICURKQAMBQBDR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Substituted nitrogen-containing heteroaryl derivatives useful as modulators of the histamine H4 receptor
  申请人：Gaul Michael D.

  公开号：US20090069305A1

  公开（公告）日：2009-03-12

  The present invention relates to substituted nitrogen-containing heteroaryl derivatives, pharmaceutical compositions containing them, and methods of using any of these derivatives and compositions for H 4 receptor activity modulation and the treatment of states mediated by histamine H 4 receptor activity.

  本发明涉及取代的含氮杂芳基衍生物、含有它们的药物组合物，以及使用这些衍生物和组合物中的任一种用于调节H4受体活性和治疗由组胺H4受体活性介导的状态的方法。
• TRIAZINE, PYRIMIDINE AND PYRIDINE ANALOGS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES
  申请人：Cmiljanovic Vladimir

  公开号：US20110275762A1

  公开（公告）日：2011-11-10

  The invention relates to novel therapeutic agents and diagnostic probes. The invention also relates to phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor triazine-, pyrimidine- and pyridine-based compoundŝ Formula (I), their stereoisomers, geometric isomers, tautomers, solvates, metabolites, N-oxide derivatives, pharmaceutically acceptable salts, and prodrugs thereof compositions of the new compounds; either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, for treating disorders mediated by lipid kinases. •Methods of using compounds of Formula (I) for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. (Formula I)

  本发明涉及新型治疗剂和诊断探针。本发明还涉及磷脂酰肌醇3-激酶（PI3K）和哺乳动物雷帕霉素靶蛋白酶（mTOR）抑制剂三嗪基、嘧啶基和吡啶基化合物̂公式（I），它们的立体异构体、几何异构体、互变异构体、溶剂化物、代谢物、N-氧化衍生物、药学上可接受的盐以及前药的组合物；新化合物的组合物，可以单独使用或与至少一种额外的治疗剂结合，与药学上可接受的载体；以及使用新化合物的方法，可以单独使用或与至少一种额外的治疗剂结合，用于治疗由脂质激酶介导的疾病。公开了使用公式（I）化合物的方法，用于哺乳动物细胞中的体外、原位和体内诊断、预防或治疗这种疾病或相关病理条件。(公式I)
• HIGH MOLECULAR COMPOUND, METHOD FOR PRODUCING SAME, AND LIGHT-EMITTING ELEMENT
  申请人：Goto Osamu

  公开号：US20130248778A1

  公开（公告）日：2013-09-26

  A polymer compound is provided for achieving satisfactory brightness even at a low driving voltage when applied to a light-emitting device. A preferred embodiment includes multiple first groups and a block (A) having a structure in which the first groups are linked by a second group represented by formula (0-0), and includes at least one of a group represented by formula (0-1) or a group represented by formula (0-2) as the first group; wherein Ar 0 represents an optionally substituted arylene group or divalent aromatic heterocyclic group having a structure different from the first group; n represents an average chain length of Ar 0 and equals 1.0 to 8.0; and X 11 to X 16 and X 21 to X 25 each represent a carbon atom or a nitrogen atom, where two or three of X 11 to X 16 are a nitrogen atom and three of X 21 to X 25 are a nitrogen atom.

  提供了一种聚合物化合物，可在低驱动电压下应用于发光装置，以实现令人满意的亮度。首选实施例包括多个第一组和一个具有结构的块(A)，其中第一组由由公式(0-0)表示的第二组连接，并且至少包括由公式(0-1)或公式(0-2)表示的一组作为第一组;其中Ar0表示结构不同于第一组的可选取代芳基或二价芳香杂环基；n表示Ar0的平均链长，等于1.0至8.0；X11到X16和X21到X25分别表示碳原子或氮原子，其中X11到X16中的两个或三个为氮原子，X21到X25中的三个为氮原子。
• POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS
  申请人：Humphries Martin J.

  公开号：US20140235800A1

  公开（公告）日：2014-08-21

  A method of forming a crosslinked polymer comprising the step of reacting a crosslinkable group in the presence of a polymer, wherein: the crosslinkable group comprises a core unit substituted with at least one crosslinkable unit of formula (I): the crosslinkable group is bound to the polymer or is a crosslinkable compound mixed with the polymer; Ar is aryl or heteroaryl which may be unsubstituted or substituted with one or more substituents independently selected from monovalent substituents and a divalent linking group linking the unit of formula (I) to the core unit; and R is independently in each occurrence H, a monovalent substituent or a divalent linking group linking the unit of formula (I) to the core unit, with the proviso that at least one R is not H.

  一种形成交联聚合物的方法，包括在聚合物存在的情况下反应交联基团，其中：交联基团包括被至少一个式(I)的交联单元取代的核心单元：交联基团与聚合物结合或与聚合物混合的交联化合物；Ar是芳基或杂芳基，可以是未取代或取代的，其中取代基可以是单价取代基和二价连接基，连接式(I)单元与核心单元连接；R在每次出现时独立地为H、单价取代基或二价连接基，除非至少有一个R不是H。
• COMPOUND FOR AN ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME
  申请人：JUNG Sung-Hyun

  公开号：US20120104941A1

  公开（公告）日：2012-05-03

  A compound for an organic photoelectric device, an organic photoelectric device, and a display device, the compound being represented by the following Chemical Formula 3a, 3b, or 3c: