2,4-Dichloro-6-(iodomethyl)-1,3,5-triazine | 30894-69-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 2,4-Dichloro-6-(iodomethyl)-1,3,5-triazine
• CAS: 30894-69-0
• 化学式: C₄H₂Cl₂IN₃
• 分子量: 289.89
• InChiKey: ZWSXGOMECQLNIQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Methods and compositions of novel triazine compounds
  申请人：Timmer T. Richard

  公开号：US20070043051A1

  公开（公告）日：2007-02-22

  The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.

  本发明涉及使用化合物治疗由炎症反应引起的病理生理状况的方法和组合物。具体而言，本发明涉及抑制或阻断糖基化蛋白诱导内皮细胞中与信号相关的炎症反应的化合物。本发明涉及抑制平滑肌增殖的化合物。具体而言，本发明涉及通过调节HSPGs（如Perlecan）来抑制平滑肌细胞增殖的化合物。本发明进一步涉及使用化合物治疗以平滑肌增殖为特征的血管闭塞性疾病，如再狭窄和动脉粥样硬化。
• SUSTAINED RELEASE OF NUTRIENTS IN VIVO
  申请人：NEW WORLD PHARMACEUTICALS, LLC

  公开号：US20140037830A1

  公开（公告）日：2014-02-06

  Nutritional compositions delivered in vivo in a time controlled manner sustainable over long periods of time, provide enhancing athletic performance, increased hand/eye coordination and concentration on the task at hand.

  营养成分能够在长时间内以时间控制的方式稳定地输送到体内，从而提高运动表现，增强手眼协调能力，并集中注意力完成手头任务。
• BONDING METHOD, BONDABILITY IMPROVING AGENT, SURFACE MODIFICATION METHOD, SURFACE MODIFYING AGENT, AND NOVEL COMPOUND
  申请人：Mori, Kunio

  公开号：EP2623572A1

  公开（公告）日：2013-08-07

  [Problem] To provide a technique by which an -OH group can be effectively formed on a material surface for the purpose of making the material suitable for bonding (for example, for molecular bonding) that utilizes a chemical reaction (chemical binding). [Solution] A bonding method for bonding a substrate A and a substrate B, which comprises: a step for applying an agent that contains the compound (α) described below on the surface of the substrate A; a step for arranging the substrate B so as to face the compound (α) that is present on the surface of the substrate A; and a step for integrally bonding the substrate A and the substrate B by applying a force onto the substrate A and/or the substrate B. The compound (α) is a compound that has an OH group or an OH-forming group, an azide group and a triazine ring in each molecule, and the substrate A is configured using a polymer.

  [问题]提供一种技术，通过该技术可以在材料表面有效地形成-OH 基团，从而使材料适于利用化学反应（化学结合）进行结合（例如，分子结合）。[解决方案]一种用于粘合基底 A 和基底 B 的粘合方法，包括：在基底 A 表面涂抹含有下述化合物 (α)的药剂的步骤；将基底 B 排列成正对基底 A 表面的化合物 (α)的步骤；以及通过在基底 A 和/或基底 B 上施加作用力来整体粘合基底 A 和基底 B 的步骤。化合物 (α)是一种在每个分子中都有一个 OH 基团或一个 OH 形成基团、一个叠氮基团和一个三嗪环的化合物，基底 A 是用聚合物配置的。
• CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE
  申请人：Samsung Electronics Co., Ltd.

  公开号：EP3184522A1

  公开（公告）日：2017-06-28

  A condensed cyclic compound, a composition including the condensed cyclic compound, an organic light-emitting device including the condensed cyclic compound, and a method of manufacturing the organic light-emitting device are provided.

  本文提供了一种缩合环状化合物、一种包括该缩合环状化合物的组合物、一种包括该缩合环状化合物的有机发光器件以及一种制造该有机发光器件的方法。
• NOVEL SEH INHIBITORS AND THEIR USE
  申请人：GlaxoSmithKline LLC

  公开号：EP2209376B1

  公开（公告）日：2013-03-06