1,4-Benzenediamine, 2-(bis(4-chlorophenyl)methyl)-N4-(3-(bis(4-chlorophenyl)methyl)-4-(dimethylamino)phenyl)-N1,N1-dimethyl- | 99123-36-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 1,4-Benzenediamine, 2-(bis(4-chlorophenyl)methyl)-N4-(3-(bis(4-chlorophenyl)methyl)-4-(dimethylamino)phenyl)-N1,N1-dimethyl-
• 英文别名: 2-[bis(4-chlorophenyl)methyl]-4-N-[3-[bis(4-chlorophenyl)methyl]-4-(dimethylamino)phenyl]-1-N,1-N-dimethylbenzene-1,4-diamine
• CAS: 99123-36-1
• 化学式: C₄₂H₃₇Cl₄N₃
• 分子量: 725.6
• InChiKey: BGFTWECWAICPDG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13
• 重原子数：
  49
• 可旋转键数：
  10
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  18.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• METHOD FOR MEASURING TRIGLYCERIDE IN LOW-DENSITY LIPOPROTEIN AND KIT FOR MEASUREMENT
  申请人：Katayama Yuki

  公开号：US20090226944A1

  公开（公告）日：2009-09-10

  The present invention provides a method for a simple and accurate measurement of triglycerides in low-density lipoprotein in a sample comprising performing the following steps sequentially: (i) a step of generating free glycerol by allowing lipoprotein lipase to act on a sample, in an aqueous medium comprising the sample and a specific surfactant such as polyoxyethylene polyoxyalkylene polycyclic phenyl ether; (ii) a step of removing free glycerol present in the reaction solution of the above step (i); (iii) a step of generating free glycerol by allowing lipoprotein lipase to act on the reaction solution from which free glycerol has been removed in step (ii), in the presence of a specific surfactant such as polyoxyethylene polyoxyalkylene alkyl ether; and (iv) a step of measuring free glycerol generated in step (iii), and a kit used for the method.

  本发明提供了一种简单准确地测量样品中低密度脂蛋白中甘油三酯的方法，包括按照以下步骤顺序进行：(i)在包括样品和特定表面活性剂（例如聚氧乙烯聚氧烷基多环苯醚）的水介质中，使脂蛋白酯酶作用于样品，生成游离甘油；(ii)去除步骤(i)中反应溶液中存在的游离甘油；(iii)在去除步骤(ii)中的游离甘油的反应溶液中，使脂蛋白酯酶作用于特定表面活性剂（例如聚氧乙烯聚氧烷基烷基醚）的存在下，生成游离甘油；(iv)测量步骤(iii)中生成的游离甘油，以及用于该方法的试剂盒。
• OXIDATIVE CHROMOGENIC COMPOUND OR SALT THEREOF AND PRODUCTION METHOD THEREOF, AND REAGENT COMPOSITION AND TEST INSTRUMENT USING THE SAME
  申请人：Kawanishi Tetsuro

  公开号：US20100062464A1

  公开（公告）日：2010-03-11

  It is an object of the present invention to provide a means for measuring a concentration of various components rapidly with high accuracy and high sensitivity. The present invention is to provide an oxidative chromogenic compound or salt thereof represented by the following chemical formula (1): wherein R 1 and R 2 are each independently a linear or branched alkyl group having 1 to 5 carbon atoms; R 3 , R 4 , R 5 , R 6 and R 7 are each independently a hydrogen atom, a carboxyl group or a sulfonic acid group, or salt thereof, provided that at least one of R 3 to R 7 is a carboxyl group or a sulfonic acid group, or salt thereof, and the others are hydrogen atoms, and the production method thereof, and the reagent composition and test instrument using the same.

  本发明的目的是提供一种快速、高精度和高灵敏度测量各种成分浓度的手段。本发明提供了一种氧化性显色化合物或其盐，其化学式如下（1）：其中R1和R2分别是具有1至5个碳原子的线性或支链烷基；R3、R4、R5、R6和R7分别是氢原子、羧基或磺酸基，或其盐，但至少其中之一是羧基或磺酸基，或其盐，其余为氢原子，以及其生产方法、试剂组成和使用该试剂组成的测试仪器。
• Method of assaying bolld component by using whole blood and measurement kit
  申请人：Umegae Yoshihiki

  公开号：US20100075352A1

  公开（公告）日：2010-03-25

  [Problem] In quickly assaying a blood component interfered by glucose and/or its derivative on the bedside or in a clinic or in assaying the same by a patient in his/her own home, there has been required an assay method wherein the whole blood can be used as a sample as such without resorting to a centrifuge or the like. [Means For Solving Problems] A method of assaying a blood component to be used for assaying a blood component interfered by glucose and/or its derivative, characterized by comprising bringing the whole blood into contact with a substance capable of converting glucose and/or its derivative into another substance not interfering the assay and, simultaneously or subsequently, separating blood cells; a device to be used in the assay method; and a kit containing this device.

  【问题】在床边或诊所中快速检测被葡萄糖和/或其衍生物干扰的血液成分，或者在患者自己的家中进行检测，需要一种检测方法，可以使用全血作为样本，而不需要离心机或类似设备。【解决问题的方法】一种检测血液成分的方法，用于检测被葡萄糖和/或其衍生物干扰的血液成分，其特征在于将全血与能够将葡萄糖和/或其衍生物转化为不干扰检测的另一种物质接触，并同时或随后分离血细胞；用于该检测方法的设备；以及包含该设备的试剂盒。
• Novel acetylpolyamine amidohydrolase
  申请人：KYOWA HAKKO KOGYO CO., LTD.

  公开号：EP0297533A2

  公开（公告）日：1989-01-04

  A novel acetylpolyamine amidohydrolase is described. The enzyme specifically hydrolyzes the amino bond in acetylputrescine, acetylcadaverine, acetylspermidine and acetylspermine with strong substrate affinity. The enzyme is preferably produced by culturing a microorganism belonging to the genus Mycoplana, and is used in the quantitative determination of polyamine contained in a living body sample, which is useful for cancer diagnosis.

  本研究描述了一种新型乙酰多胺酰胺水解酶。该酶能特异性地水解乙酰泼尼松碱、乙酰金刚烷胺、乙酰精胺和乙酰精胺中的氨基键，具有很强的底物亲和力。该酶最好是通过培养属于霉浆菌属的微生物产生的，可用于定量测定活体样本中含有的多胺，这对癌症诊断非常有用。
• Method for enzymatic determination of substrate after enzymatically removing galactose
  申请人：Kyowa Medex Co. Ltd.

  公开号：EP0608795A1

  公开（公告）日：1994-08-03

  According to the present invention, there is provided a method for the accurate quantitative determination of a specific component in a samples which contains galactose by enzymes. The method is characterized in that, prior to said quantitative determination, galactose in the sample is subjected to an enzyme reaction in which galactose is used as a substrate.

  根据本发明，提供了一种用酶精确定量测定含半乳糖样品中特定成分的方法。 该方法的特点是，在进行上述定量测定之前，先将样品中的半乳糖作为底物进行酶反应。