Β-1,4-半乳糖基转移酶来源于牛奶 | 9030-11-9

• 分子结构分类: 转移酶 - 糖基转移酶 - 己糖基转移酶
• 中文名称: Β-1,4-半乳糖基转移酶来源于牛奶
• 中文别名: 乳糖合成酶
• 英文名称: lactose synthase
• 英文别名: UDP-galactose---glucose galactosyltransferase；N-acetyllactosamine synthase；uridine diphosphogalactose-glucose galactosyltransferase；lactose synthetase；UDP-galactose:D-glucose 4-beta-D-galactotransferase；UDP-galactose:D-glucose 4-beta-D-galactosyltransferase；β-D-galactosyltransferase
• CAS: 9030-11-9

反应信息

• 作为试剂：
  描述：

  1,10-Di-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl)-2-azi-1,10-decanediol 在 Β-1,4-半乳糖基转移酶来源于牛奶 sodium methylate 作用下， 以 甲醇 、 水 为溶剂， 反应 2.0h， 生成
  参考文献：
  名称：

  A spacer-modified disaccharide as a photoaffinity reagent for the acceptor-binding area of bovine (1 → 4)-β-d-galactosyltransferase: comparison of its acceptor properties with those of other 2-acetamido-2-deoxy-β-d-glucopyranosides

  摘要：

  The spacer-modified disaccharide 1,10-di-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-2-azi-1,10-decanediol (10) that mimics the biantennary. core heptasaccharide of N-glycoproteins has been synthesised. Compound 10 is an excellent acceptor in galactosyltransferase-catalysed galactosylation by UDP-galactose, is superior (7-8-fold) to analogues that have only one GlcNAc unit, and is an efficient photoaffinity reagent for galactosyltransferase. In the presence of UDP-Gal. no photoaffinity labelling by 10 takes place, which agrees the mechanism of galactosyltransferase action.

  DOI：

  10.1016/s0008-6215(00)90925-x