三(甲基硒)甲烷 | 66622-20-6

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 中文名称: 三(甲基硒)甲烷
• 英文名称: trimethyl orthoselenoformate
• 英文别名: triselenoorthoformic acid trimethyl ester；Triselenoorthoameisensaeure-trimethylester；Tris(methylselanyl)methane
• CAS: 66622-20-6
• 化学式: C₄H₁₀Se₃
• 分子量: 295.003
• InChiKey: JIYFVZBIPMSBSX-UHFFFAOYSA-N

物化性质

• 稳定性/保质期：
  遵照规定使用和储存，则不会分解。

计算性质

• 辛醇/水分配系数(LogP)：
  1.98
• 重原子数：
  7
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 危险品标志：
  T,N-T,N
• 安全说明：
  S20/21,S28,S45,S60,S61
• 危险类别码：
  R50/53,R23/25,R33
• 海关编码：
  2901100000

SDS

Name:	Tris(methylseleno)methane Material Safety Data Sheet
Synonym:	None
CAS:	66622-20-6

Section 1 - Chemical Product MSDS Name:Tris(methylseleno)methane Material Safety Data Sheet
Synonym:None

---

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
66622-20-6	TRIS(METHYLSELENO)METHANE	ca 100	unlisted

Hazard Symbols: T
Risk Phrases: 23/25 33

---

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic by inhalation and if swallowed. Danger of cumulative effects.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May cause alopecia (loss of hair). May cause central nervous system effects. May cause kidney, liver and spleen damage. May cause garlic smell on the breath and body.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May cause spleen and liver damage. May cause central, peripheral, and autonomic nervous system effects.
Chronic:
Chronic exposure to selenium may cause central nervous system effects, digestive tract disturbances, pallor, garlic breath, Chronic exposure to selenium may cause pallor, garlic breath, metallic taste, anemia, liver and spleen damage. Chronic selenium poisoning is characterized by loss of hair and nails, skin lesions, and abnormalities of the nervous system.

---

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician:

---

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

---

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

---

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use only in a chemical fume hood.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.)

---

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 66622-20-6: United Kingdom, WEL - TWA: (listed as selenium compounds): 0.1 mg TWA (except hydrogen selenide, as Se) United Kingdom, WEL - STEL: (listed as selenium compounds): 0.3 m STEL (except hydrogen selenide, as Se) United States OSHA: 0.2 mg/m3 TWA (as Se) (listed under Selenium compounds).
Belgium - TWA: (listed as selenium compounds): 0.2 mg/m3 VLE (as Japan: (listed as selenium compounds): 0.1 mg/m3 OEL (except SeH2 SeF6, as Se) Malaysia: (listed as selenium compounds): 0.2 mg/m3 TWA (as Se) Netherlands: (listed as selenium compounds): 0.1 mg/m3 MAC (as Se Spain: (listed as selenium compounds): 0.1 mg/m3 VLA-ED (except hydrogen selenide, as Se) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

---

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white to off-white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C4H10Se3
Molecular Weight: 295.00

---

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, selenium/selenium oxides.
Hazardous Polymerization: Has not been reported.

---

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 66622-20-6 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
TRIS(METHYLSELENO)METHANE - Not listed by ACGIH, IARC, or NTP.

---

Section 12 - ECOLOGICAL INFORMATION

---

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

---

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: SELENIUM COMPOUND, N.O.S.
Hazard Class: 6.1
UN Number: 3283
Packing Group: II
IMO
Shipping Name: SELENIUM COMPOUND, N.O.S.
Hazard Class: 6.1
UN Number: 3283
Packing Group: II
RID/ADR
Shipping Name: SELENIUM COMPOUND, N.O.S.
Hazard Class: 6.1
UN Number: 3283
Packing group: II

---

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 23/25 Toxic by inhalation and if swallowed.
R 33 Danger of cumulative effects.
Safety Phrases:
S 20/21 When using do not eat, drink or smoke.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 66622-20-6: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 66622-20-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 66622-20-6 is not listed on the TSCA inventory.
It is for research and development use only.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  三(甲基硒)甲烷 在 potassium permanganate 、 硫酸 作用下， 生成 bis-methaneselenonyl-methane
  参考文献：
  名称：

  Baroni, Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1940, vol. <7>1, p. 545

  摘要：

  DOI：
• 作为产物：
  描述：

  甲基硒基 、 原甲酸三乙酯 在 三氟化硼乙醚 作用下， 反应 16.0h， 以81%的产率得到三(甲基硒)甲烷
  参考文献：
  名称：

  .alpha.-硒碳鎓离子：制备、X 射线分子结构测定以及质子和碳 13 NMR 光谱表征

  摘要：

  Les sels des ions bis-methylselenocarbenium RC + (SeMe) 2 Y − (R=H 1 Et, PhCH 2 ; Y=BF 4 , SbCl 6 ) ainsi que leurs 类似物双甲硫醇制备三硒和三硫代原酸酯等反应avec l'ion tritylium soit avec un sel d'argent appproprie dans le dichloromethane

  DOI：

  10.1021/ja00325a012

文献信息

• New synthetic routes to vinyl sulfides, ketene thioacetals and their seleno analogues from carbonyl compounds
  作者：J.N. Denis、S. Desauvage、L. Hevesi、A. Krief

  DOI：10.1016/s0040-4039(01)82051-7

  日期：1981.1

  Title compounds have been prepared from carbonyl compounds by formal removal of hydroxyl and sulfenyl or hydroxyl and selenyl moieties from the corresponding functionalized β-hydroxysulfides or β-hydroxyselenides.

  通过从相应的官能化的β-羟基硫化物或β-羟基硒化物中正式除去羟基和亚磺酰基或羟基和硒烯基部分，已经从羰基化合物制备了标题化合物。
• 1,1-Bis(phenylseleno)- and 1,1-bis(methylseleno)-alkyllithiums as building blocks in organic synthesis
  作者：D. Van Ende、A. Cravador、A. Krief

  DOI：10.1016/s0022-328x(00)92325-8

  日期：1979.9
• Hevesi, L.; Nsunda, K. M.; Renard, M., Bulletin des Societes Chimiques Belges, 1985, vol. 94, # 11-12, p. 1039 - 1044
  作者：Hevesi, L.、Nsunda, K. M.、Renard, M.

  DOI：——

  日期：——
• Synthesis of α-silylselenoalkyllithiums
  作者：D. Van Ende、W. Dumont、A. Krief

  DOI：10.1016/s0022-328x(00)90385-1

  日期：1978.4
• ENDE D. VAN; CRAVADOR A.; KRIEF A., J. ORGANOMETAL. CHEM., 1979, 177, NO 1, 1-4
  作者：ENDE D. VAN、 CRAVADOR A.、 KRIEF A.

  DOI：——

  日期：——