二丙基次膦酸 | 867-33-4

• 分子结构分类: 有机化合物 - 有机磷化合物
• 中文名称: 二丙基次膦酸
• 英文名称: dipropylphosphinic acid
• 英文别名: Dipropyl-phosphinsaeure；di-n-propylphosphinic acid
• CAS: 867-33-4
• 化学式: C₆H₁₅O₂P
• 分子量: 150.158
• InChiKey: WMDPJKZHARKRQI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  二丙基次膦酸 在 五氯化磷 作用下， 生成 bis(dipropylphosphinic) anhydride
  参考文献：
  名称：

  The Anhydrides of Di-n-propyl- and Di-n-butyl-phosphinic Acids

  摘要：

  DOI：

  10.1021/ja01153a015
• 作为产物：
  描述：

  Tetra-n-propyl-diphosphan 在 水 作用下， 以 乙腈 为溶剂， 生成 二丙基次膦酸
  参考文献：
  名称：

  Appel,R.; Milker,R., Chemische Berichte, 1974, vol. 107, p. 2658 - 2670

  摘要：

  DOI：

文献信息

• Synthesis of alkyl phosphinic acids from silyl phosphonites and alkyl halides
  作者：E.Andrew Boyd、Andrew C. Regan、Keith James

  DOI：10.1016/s0040-4039(00)73157-1

  日期：1994.6

  Mono- and di-substituted phosphinic acids have been synthesised in a one-pot reaction, by the addition of alkyl halides to silyl phosphonites, under mild and flexible conditions.

  通过在温和而灵活的条件下，将烷基卤加入甲硅烷基亚膦酸酯中，通过一锅法反应合成了单取代和二取代的次膦酸。
• Novel cyclic diamine compounds and medicine containing the same
  申请人：Kowa Company, Ltd.

  公开号：US20040038987A1

  公开（公告）日：2004-02-26

  The present invention offers novel cyclic diamine compounds and a pharmaceutical composition containing the same. The present invention relates to a compound represented by the formula (I) or salt(s) or solvate(s) thereof. 1 (In the formula, 2 is an optionally substituted divalent residue of benzene, pyridine, cyclohexane or naphthalene or is a vinylene group where Ar is an optionally substituted aryl group; X is —NH—, oxygen atom or sulfur atom; Y is —NR 1 —, oxygen atom, sulfur atom, sulfoxide or sulfone; Z is a single bond or —NR 2 —; R 1 is hydrogen atom, optionally substituted lower alkyl group, optionally substituted aryl group or optionally substituted silyl lower alkyl group; R 2 is hydrogen atom, optionally substituted lower alkyl group, optionally substituted aryl group or optionally substituted silyl lower alkyl group; l is an integer of from 0 to 15; m is an integer of 2 or 3; and n is an integer of from 0 to 3). The compound of the present invention is useful as a pharmaceutical composition, particuarly as an inhibitor of acyl coenzyme A cholesterol acyltransferase (ACAT).

  本发明提供了新颖的环状二胺化合物以及含有该化合物的药物组合物。本发明涉及由式(I)表示的化合物或其盐或溶剂化合物。(在该式中，2是苯、吡啶、环己烷或萘的可选择取代的二价残基，或者是Ar为可选择取代芳基的乙烯基；X为—NH—、氧原子或硫原子；Y为—NR1—、氧原子、硫原子、亚砜或砜；Z为单键或—NR2—；R1为氢原子、可选择取代的较低烷基、可选择取代的芳基或可选择取代的硅烷较低烷基；R2为氢原子、可选择取代的较低烷基、可选择取代的芳基或可选择取代的硅烷较低烷基；l为0到15的整数；m为2或3的整数；n为0到3的整数)。本发明的化合物可用作药物组合物，特别是作为酰辅酶A胆固醇酰基转移酶(ACAT)的抑制剂。
• [EN] TRIFUNCTIONAL ADDITIVES FOR ELECTROLYTE COMPOSITION FOR LITHIUM BATTERIES<br/>[FR] ADDITIFS TRIFONCTIONNELS POUR COMPOSITION ÉLECTROLYTIQUE POUR BATTERIES AU LITHIUM
  申请人：BASF SE

  公开号：WO2018134251A1

  公开（公告）日：2018-07-26

  An electrolyte composition containing (i) at least one aprotic organic solvent; (ii) at least one conducting salt; (iii) at least one compound of formula (I); and (iv) optionally one or more additives.

  一种电解质组合物，包含（i）至少一种无水有机溶剂；（ii）至少一种导电盐；（iii）至少一种化学式（I）的化合物；和（iv）可选地一种或多种添加剂。
• Subphthalocyanine derivative having phosphorus derivative as axially substituted group, method for manufacturing the same and optical film using the same
  申请人：Mori Tomohiro

  公开号：US20100036134A1

  公开（公告）日：2010-02-11

  A novel subphthalocyanine derivative having a phosphorus derivative-substituted group as an axially substituted group which has an excellent solubility, a method for producing the same and an optical film containing the same, are provided without impairing excellent properties peculiar to the original subphthalocyanines. The novel subphthalocyanine derivative is represented by the following chemical formula (1), and it is applicable for optical films.

  提供一种新型的次酞菁衍生物，其具有磷衍生物取代基作为轴向取代基，具有优异的溶解性，提供了一种生产该衍生物的方法，以及含有该衍生物的光学薄膜，而不损害原始次酞菁独特性能。该新型次酞菁衍生物由以下化学式（1）表示，适用于光学薄膜。
• Mixtures of at least one dialkylphosphinic acid with at least one other dialkylphosphinic acid that is different therefrom, method for production thereof, and use thereof
  申请人：Clariant International Ltd.

  公开号：US10246640B2

  公开（公告）日：2019-04-02

  Mixtures of at least one dialkylphosphinic acid with at least one other dialkylphosphinic acid that is different therefrom, method for production thereof, and use thereof. The invention relates to a mixture of at least one dialkylphosphinic acid of the formula (I) in which R1, R2 are the same or different and are each C1-C18-alkyl, C2-C18-alkenyl, C6-C18-aryl, C7-C18-alkylaryl, with at least one different dialkylphosphinic acid of the formula (II) in which R3, R4 are the same or different and are each C1-C18-alkyl, C2-C18-alkenyl, C6-C18-aryl and/or C7-C18-alkylaryl, with the proviso that at least one of the R3 and R4 radicals is different than R1 and R2.

  至少一种二烷基膦酸与至少一种与之不同的其他二烷基膦酸的混合物，其生产方法和用途。本发明涉及至少一种具有以下结构的二烷基膦酸的混合物（I）其中R1、R2相同或不同，每个都是C1-C18烷基、C2-C18烯基、C6-C18芳基、C7-C18烷基芳基，与至少一种不同的具有以下结构的二烷基膦酸（II）其中R3、R4相同或不同，每个都是C1-C18烷基、C2-C18烯基、C6-C18芳基和/或C7-C18烷基芳基，但R3和R4中至少有一个基团与R1和R2不同。