二甲基锡(++) | 16408-14-3

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机过渡后金属化合物
• 中文名称: 二甲基锡(++)
• 英文名称: dimethyltin(IV) cation
• 英文别名: dimethyltin(IV)；Me2Sn(2+)；Dimethylzinn²⁺；Dimethylstannylkation；Dimethylzinnkation；Dimethylstannan；Dimethyltin(2)；dimethyltin(2+)
• CAS: 16408-14-3
• 化学式: C₂H₆Sn
• 分子量: 148.78
• InChiKey: VSCACQAYZDJOOU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.79
• 重原子数：
  3
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2931900090

反应信息

• 作为反应物：
  描述：

  二甲基锡(++) 、 1-[(2R)-2-甲基-3-疏基丙酰基]脯氨酸 在 NaClO₄ 作用下， 以 水 为溶剂， 生成
  参考文献：
  名称：

  Coordination properties of the ACE inhibitor captopril towards Me2Sn(IV)2+ in aqueous solution, and biological aspects of some dialkyltin(IV) derivatives of this ligand

  摘要：

  The coordination of Me2Sn(IV)(2+) (=M) to captopril {N-[(S)-3-mercapto-2-methylpropionyl]-L-proline, = H-2(cap), H2L} in aqueous solution was studied by means of potentiometric titration, electrospray mass spectrometry, H-1-NMR spectroscopy and Mossbauer spectroscopy in the pH range 2-11 (I = 0.1 mol dm(-3) NaClO4, 298 K). The results obtained with these methods proved that only monomeric complexes are formed in solution. In the acidic pH range, species with a metal-to-ligand ratio of 1:1 exist. The neutral complex ML, similarly to the complex Me2Sn(cap) crystallized in the same pH range, adopts a tbp structure with eq -S- and ax -COO-, while, instead of the coordination of the amide -C=O, observed in the solid state, the other ax position is occupied by a H2O molecule. With increasing pH, in the neutral and weakly basic pH range the complexes MLH-1 and ML2 are formed, in which the -COO- group is displaced from the coordination sphere by an OH- and an S- of another ligand, respectively. Biological activity tests on Me2Sn(cap) and three further R2Sn(IV) captopril complexes showed that n-Bu2Sn(cap) and t-Bu2Sn(cap) exert toxic activity towards the embryos of Ciona intestinalis, while the ligand itself does not affect the development of the embryos to any significant extent; Me2Sn(cap) and Et2Sn(cap) produced normal swimming larvae. (C) 2003 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(03)00015-9
• 作为产物：
  描述：

  甲基锡烷 在 氟磺酸 作用下， 以 氟磺酸 为溶剂， 生成 二甲基锡(++)
  参考文献：
  名称：

  Birchall, Thomas; Manivannan, Veeragathy, Journal of the Chemical Society, Dalton Transactions, 1985, p. 2671 - 2676

  摘要：

  DOI：