pentacarbonyl(1-(methylethoxy)ethylidene)chromium

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: pentacarbonyl(1-(methylethoxy)ethylidene)chromium
• 英文别名: Carbon monoxide;1-propan-2-yloxyethylidenechromium
• 化学式: C₁₀H₁₀CrO₆
• 分子量: 278.182
• InChiKey: UFGISCJPTCJYNH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.92
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  14.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  四甲基铵(1-羟基亚乙基)五羰基铬 、 diphenylisopropylsulfonium tetrafluoroborate 以 二氯甲烷 为溶剂， 以92%的产率得到pentacarbonyl(1-(methylethoxy)ethylidene)chromium
  参考文献：
  名称：

  用锍盐制备铬、钼和钨的烷氧基卡宾配合物的新方法

  摘要：

  铬、钼和钨的四甲基酰化铵配合物与烷基二苯基锍盐的烷基化反应在温和条件下很容易进行，以良好的产率得到含有多种官能团的烷氧基卡宾配合物。

  DOI：

  10.1246/cl.1994.1537

文献信息

• Preparation of Fischer carbene complexes by alkylation of acylmetalates with alkyl iodides
  作者：Thomas R. Hoye、Kejian Chen、James R. Vyvyan

  DOI：10.1021/om00031a056

  日期：1993.7

  Neutral Fischer carbene complexes bearing alkoxy groups as the donor substituents on the carbene carbon atom have been synthesized by direct alkylation of the lithium acylmetalates (formed by classical addition of organolithium compounds to metal hexacarbonyl) by alkyl iodides. It was shown that the reaction proceeds under normal phase-transfer conditions (CH2-Cl2/H2O) or, preferably, in aqueous medium alone. However, in both cases the presence of a catalytic amount of a tetraalkylammonium salt (n-Bu4NBr) was required. Attractive features of this methodology are (i) the economy of using alkyl iodides in place of the usual alkylating agents (like Me3O+BF4-, magic methyl, or methyl triflate), (ii) the procedural ease of ''one-pot'' preparation of the carbene complexes, and (iii) the greater variety of alkyl moieties that can be incorporated as part of the alkoxy substituent using the more readily available alkyl iodides containing nontrivial alkyl groups. The procedure is preparatively useful for accessing chromium-containing carbenes, but yields of the analogous molybdenum- and tungsten-containing species are only less-than-or-equal-to 10%. Mechanistic considerations suggest that products are formed by competing pathways involving direct S(N)2 displacement vs electron-transfer-initiated S(RN)1 processes.
• New Method for the Preparation of Alkoxycarbene Complexes of Chromium, Molybdenum, and Tungsten Using Sulfonium Salts
  作者：Takako Nakamura、Haruo Matsuyama、Masahiko Iyoda

  DOI：10.1246/cl.1994.1537

  日期：1994.8

  Alkylation of tetramethylammonium acylate complexes of chromium, molybdenum, and tungsten with alkyldiphenylsulfonium salts readily proceeds under mild conditions to afford alkoxycarbene complexes containing a variety of functional groups in good yields.

  铬、钼和钨的四甲基酰化铵配合物与烷基二苯基锍盐的烷基化反应在温和条件下很容易进行，以良好的产率得到含有多种官能团的烷氧基卡宾配合物。