3-triphenylmethylthio-2-chloromethylpyridine | 792177-61-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 3-triphenylmethylthio-2-chloromethylpyridine
• 英文别名: 2-(Chloromethyl)-3-tritylsulfanylpyridine
• CAS: 792177-61-8
• 化学式: C₂₅H₂₀ClNS
• 分子量: 401.96
• InChiKey: PRXKRCGINXBXBM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.5
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  38.2
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBOXYLIC ACID ANTIBIOTICS AND PRODRUGS THEREOF
  申请人：Essential Therapeutics, Inc.

  公开号：EP1222194A1

  公开（公告）日：2002-07-17
• US6723716B1
  申请人：——

  公开号：US6723716B1

  公开（公告）日：2004-04-20
• [EN] 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBOXYLIC ACID ANTIBIOTICS AND PRODRUGS THEREOF<br/>[FR] ANTIBIOTIQUES A L'ACIDE 7-ACYLAMINO-3-HETEROARYLTHIO-3-CEPHEM CARBOXYLIQUE ET PROMEDICAMENTS DE CES DERNIERS
  申请人：MICROCIDE PHARMACEUTICALS INC

  公开号：WO2001021623A1

  公开（公告）日：2001-03-29

  The present invention includes novel (7R)-7-acylamino-3-heteroarylthio-3-cephem-4-carboxylic acids or their pharmacologically acceptable salts and prodrugs thereof, which exhibit antibiotic activity against a wide spectrum of organisms including organisms which are resistant to β-lactam antibiotics and are useful as antibacterial agents. The invention also relates to novel intermediates useful for making the novel compounds of the present invention and to novel methods for producing the novel compounds and intermediate compounds.