2-Acenaphthylen-5-yl-1-(4-methoxynaphthalen-1-yl)guanidine

• 分子结构分类: 有机化合物 - 苯类化合物 - 吖萘类
• 英文名称: 2-Acenaphthylen-5-yl-1-(4-methoxynaphthalen-1-yl)guanidine
• 化学式: C₂₄H₁₉N₃O
• 分子量: 365.4
• InChiKey: RZCWHDYNSGVBFW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  59.6
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Methods of treatment of eye trauma and disorders
  申请人：——

  公开号：US20030027801A1

  公开（公告）日：2003-02-06

  Methods are provided for treatment of eye disorders and injury, including methods for treatment of reduced flow of blood or other nutrients to retinal tissue and/or optic nerve, methods for treatment of retinal ischemia and trauma and methods for treatment for optic nerve injury/damage.

  提供了治疗眼部疾病和损伤的方法，包括治疗流向视网膜组织和/或视神经的血液或其他营养物质减少的方法、治疗视网膜缺血和创伤的方法以及治疗视神经损伤/损坏的方法。
• Sodium channel blocker compositions and the use thereof
  申请人：——

  公开号：US20040054005A1

  公开（公告）日：2004-03-18

  Methods of treating or preventing chronic pain or convulsion are disclosed by administering to an animal a sodium channel blocker and at least one of gabapentin and pregabalin. Also disclosed are pharmaceutical compositions and kits for the treatment or prevention of chronic pain or convulsion.

  本发明公开了通过向动物施用钠通道阻滞剂以及加巴喷丁和普瑞巴林中的至少一种来治疗或预防慢性疼痛或抽搐的方法。还公开了用于治疗或预防慢性疼痛或抽搐的药物组合物和试剂盒。
• Dispersible formulation of an anti-inflammatory agent
  申请人：Britten Jean Nancy

  公开号：US20050004098A1

  公开（公告）日：2005-01-06

  A method is provided for treatment and/or prevention of an inflammatory condition in a fluid-containing organ having a natural exterior orifice, such as the udder of a milk-producing animal or an ear of a subject. The invention also relates to a dispersible pharmaceutical composition suitable for infusion into the organ according to the method of the invention, and a process for preparing such a composition.

  本发明提供了一种方法，用于治疗和/或预防具有天然外部孔口的含液器官的炎症，例如产奶动物的乳房或受试者的耳朵。本发明还涉及一种适用于根据本发明方法注入器官的可分散药物组合物，以及制备这种组合物的工艺。
• SUBSTITUTED GUANIDINES AND DERIVATIVES THEREOF AS MODULATORS OF NEUROTRANSMITTER RELEASE AND NOVEL METHODOLOGY FOR IDENTIFYING NEUROTRANSMITTER RELEASE BLOCKERS
  申请人：CAMBRIDGE NEUROSCIENCE RESEARCH, INC.

  公开号：EP0584088A1

  公开（公告）日：1994-03-02
• EP0584088A4
  申请人：——

  公开号：EP0584088A4

  公开（公告）日：1995-01-18