苊烯-1-甲醛 | 96462-56-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 吖萘类
• 中文名称: 苊烯-1-甲醛
• 英文名称: Acenaphthylene-1-carboxaldehyde
• 英文别名: acenaphthylene-1-carbaldehyde；Acenaphthylen-1-carbaldehyd；acenapthylene-1-carboxaldehyde；acenaphtalene；Acenaphthylen-1-carboxaldehyd
• CAS: 96462-56-5
• 化学式: C₁₃H₈O
• 分子量: 180.206
• InChiKey: DJGQYTUXTCURSC-UHFFFAOYSA-N

物化性质

• 沸点：
  196 °C(Press: 14 Torr)
• 密度：
  1.357±0.06 g/cm3(Predicted)
• 保留指数：
  303.4

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  苊烯-1-甲醛 在 sodium tetrahydroborate 作用下， 以 甲醇 、 乙醇 为溶剂， 反应 0.5h， 以85%的产率得到acenaphthylen-1-ylmethanol
  参考文献：
  名称：

  An Efficient Synthesis of 1-Substituted Acenaphthylenes and Acenaphthenes, Synthesis of Acenaphthene-1-carboxylic acid

  摘要：

  DOI：

  10.1021/jo00099a047
• 作为产物：
  描述：

  1-bromoacenaphthylene 以90%的产率得到
  参考文献：
  名称：

  Haddad Nizar, Abu-Shqara Elias, J. Org. Chem., 59 (1994) N 20, S 6090-6092

  摘要：

  DOI：

文献信息

• 1,5-benzodiazepine compounds, their production and use
  申请人：——

  公开号：US20030149027A1

  公开（公告）日：2003-08-07

  A compound represented by the formula (I) 1 [wherein ring B represents a cyclic hydrocarbon group which may have substituent(s); Z represents hydrogen atom or a cyclic group which may have substituent(s); R 1 represents hydrogen atom, a hydrocarbon group which may have substituent(s), a heterocyclic group which may have substituent(s) or an acyl group; R 2 represents amino group which may have substituent(s); D represents a bond or a divalent group; E represents a bond, —CO—, —CON(R a )—, —COO—, —N(R a )CON(R b )—, —N(R a )COO—, —N(R a )SO 2 —, —N(R a )—, —O—, —S—, —SO— or —SO 2 — (R a and R b each independently represents hydrogen atom or a hydrocarbon group which may have substituent(s)); G represents a bond or a divalent group; L represents a bond or a divalent group; A represents hydrogen atom or a substituent; X and Y each represents hydrogen atom or an independent substituent; and . . . represents that R 2 and an atom on ring B may form a ring] or a salt thereof, and a process for producing the same.

  化合物的化学式为（I） 其中，环B代表可能具有取代基的环烃基团；Z代表氢原子或可能具有取代基的环基团；R1代表氢原子、可能具有取代基的烃基团、可能具有取代基的杂环基团或酰基；R2代表可能具有取代基的氨基团；D代表键或二价基团；E代表键、—CO—、—CON(Ra)—、—COO—、—N(Ra)CON(Rb)—、—N(Ra)COO—、—N(Ra)SO2—、—N(Ra)—、—O—、—S—、—SO—或—SO2—（Ra和Rb各自独立代表氢原子或可能具有取代基的烃基团）；G代表键或二价基团；L代表键或二价基团；A代表氢原子或取代基；X和Y各自代表氢原子或独立的取代基；以及...代表R2和环B上的一个原子可能形成环，或其盐，以及其制备方法。
• [EN] HETEROARYLS AND THEIR USE AS PI3K INHIBITORS<br/>[FR] HÉTÉROARYLES ET APPLICATIONS ASSOCIÉES
  申请人：MILLENNIUM PHARM INC

  公开号：WO2010090716A1

  公开（公告）日：2010-08-12

  This invention provides compounds of formula (IA) or (IB): wherein R1, R2, G1 and HY are as described in the specification. The compounds are inhibitors of PI3K and/or mTor and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.

  这项发明提供了式（IA）或（IB）的化合物：其中R1、R2、G1和HY如规范中所述。这些化合物是PI3K和/或mTor的抑制剂，因此可用于治疗增殖性、炎症性或心血管疾病。
• Fused Heterocyclic Compound
  申请人：Ishikawa Tomoyasu

  公开号：US20070244132A1

  公开（公告）日：2007-10-18

  The present invention relates to a compound represented by the formula: wherein W is C(R 1 ) or N, each A is an optionally substituted aryl group or a heteroaryl group, X 1 is —NR 3 —Y 1 —, —O—, —S—, —SO—, —SO 2 — or —CHR 3 — wherein R 3 is a hydrogen atom or an optionally substituted aliphatic hydrocarbon group, or R 3 is optionally bonded to A to form an optionally substituted ring structure, R 1 is a hydrogen atom or an optionally substituted group bonded via a carbon atom, a nitrogen atom or an oxygen atom, R 2 is a hydrogen atom or optionally substituted group bonded via a carbon atom or a sulfur atom, or R 1 and R 2 , or R 2 and R 3 are optionally bonded to form an optionally substituted ring structure, or a salt thereof, and a tyrosine kinase inhibitor or an agent for the prophylaxis or treatment of cancer, which contains this compound or a prodrug thereof.

  本发明涉及一种化合物，其表示式为：其中W是C（R1）或N，每个A是可选取代的芳基或杂环基，X1是—NR3—Y1—、—O—、—S—、—SO—、—SO2—或—CHR3—，其中R3是氢原子或可选取代的脂肪烃基，或者R3与A可选地结合形成可选取代的环状结构，R1是氢原子或通过碳原子、氮原子或氧原子键合的可选取代基团，R2是氢原子或通过碳原子或硫原子键合的可选取代基团，或者R1和R2，或者R2和R3可选地键合形成可选取代的环状结构，或其盐，以及含有该化合物或其前药的酪氨酸激酶抑制剂或预防或治疗癌症的药物。
• Method of manufacturing a semiconductor device
  申请人：Oguro Dai

  公开号：US20070059632A1

  公开（公告）日：2007-03-15

  The compound of the present invention is represented by the following formula 1: wherein R 1 , R 2 , R 4 , R 5 , m0 to m2, and n0 to n2 are as defined in the description. Radiation sensitive compositions containing the compound of the formula 1 as a main component of the solid component are excellent in sensitivity, resolution, heat resistance, etching resistance, and solubility in solvent.

  本发明的化合物由以下的公式1表示：其中，R1、R2、R4、R5、m0至m2和n0至n2的定义如描述中所述。含有公式1化合物作为固体组分主要成分的辐射敏感组合物在敏感性、分辨率、耐热性、耐蚀性和溶解度方面表现出色。
• AROMATIC RING-CONTAINING POLYMER FOR UNDERLAYER OF RESIST AND RESIST UNDERLAYER COMPOSITION INCLUDING THE SAME
  申请人：KIM Min-Soo

  公开号：US20120270994A1

  公开（公告）日：2012-10-25

  An aromatic ring-containing polymer for an underlayer of a resist, including a unit structure represented by Chemical Formula 1:

  一种含有芳香环的聚合物，用于光刻胶的底层，包括由化学式1表示的单元结构。