1-[(2-chlorophenyl)-diphenylmethyl]imidazole;(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 1-[(2-chlorophenyl)-diphenylmethyl]imidazole;(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
• 化学式: C40H50Cl2N4O5S
• 分子量: 769.8
• InChiKey: YIYNXDLITAJQRH-ZCHRUFPLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.77
• 重原子数：
  52
• 可旋转键数：
  11
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  145
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• Dermatological compositions
  申请人：Stockel F. Richard

  公开号：US20050136024A1

  公开（公告）日：2005-06-23

  This invention discloses new and novel dermatological compositions synthesized by a metathesis or an acid-base reaction, where both reactants have bioactivity, resulting in improved properties for the treatment of various skin conditions. The novel compositions are preventive as well as therapeutic in alleviating the symptoms of skin disorders associated with disturbed keratinzation or inflammation.