无水蔡斯盐 - CAS号 12012-50-9

物化性质

密度：

2.880
稳定性/保质期：

遵照规格使用和储存则不会分解。

计算性质

辛醇/水分配系数(LogP)：

-11.18
重原子数：

7
可旋转键数：

0
环数：

0.0
sp3杂化的碳原子比例：

0.0
拓扑面积：

0
氢给体数：

0
氢受体数：

3

安全信息

危险类别码：

R36/37/38
储存条件：

密封于阴凉干燥处保存。

SDS

SDS：279e04ef46b1be6f54dd5dc5eff7ee2f

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Name:	Potassium trichloro(ethylene)platinate(ii) monohydrate Material Safety Data Sheet
Synonym:	Zeise's sal
CAS:	12012-50-9

Section 1 - Chemical Product MSDS Name:Potassium trichloro(ethylene)platinate(ii) monohydrate Material Safety Data Sheet
Synonym:Zeise's sal

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
12012-50-9	Potassium trichloro(ethylene)platinate		234-577-7

Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.Hygroscopic (absorbs moisture from the air).
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
Causes respiratory tract irritation.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. Get medical aid if cough or other symptoms appear.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.
Exposure Limits CAS# 12012-50-9: United States OSHA: 0.002 mg/m3 TWA (as Pt) (listed under Platin soluble salts).
Belgium - TWA: (listed as platinum soluble salts): 0.002 mg/m3 VL (as Pt) Japan: (listed as platinum soluble salts): 0.001 mg/m3 OEL (as Pt Malaysia: (listed as platinum soluble salts): 0.002 mg/m3 TWA (as Netherlands: (listed as platinum soluble salts): 0.002 mg/m3 MAC Pt) Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear a chemical apron.
Respirators:
A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: yellow-green
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 220 deg C dec
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C2H4Cl3KPt.H2O
Molecular Weight: 386.60

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 12012-50-9: TP1880000 LD50/LC50:
Not available.
Carcinogenicity:
Potassium trichloro(ethylene)platinate(II) monohydrate - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 12012-50-9: No information available.
Canada
CAS# 12012-50-9 is listed on Canada's NDSL List.
CAS# 12012-50-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 12012-50-9 is listed on the TSCA inventory.

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

作为反应物：

描述：

无水蔡斯盐在吡啶作用下，以水为溶剂，生成 pyridine-dichloro-(ethylene)-platinum(II)

参考文献：

名称：

的反应的反式-二氯（乙烯）pyridineplatinum（II）与取代的吡啶和乙烯复合物：在配体交换和游离碱的攻击的机构的协调烯烃。制备两种含铂碳键的两性离子络合物

摘要：

通过游离胺对反式的配位乙烯的亲核攻击，制备了两种式为反式-[Pt（CH 2 CH 2 L）Cl 2 L]（L = 4-甲基吡啶或3,5-二甲基吡啶）的配合物-[Pt（C 2 H 4）Cl 2 L]。这样的反应仅在碱性较高且受阻较少的吡啶中发生。游离吡啶还对金属中心表现出亲核攻击，从而导致吡啶交换反应。对于所有吡啶，交换过程中活化的自由能为<42 kJ mol –1，其中2,4,6-三甲基吡啶的活化自由能为> 80 kJ mol –1。在游离乙烯的存在下，发生游离烯烃与络合烯烃之间的交换。同样在这种情况下，交换过程是通过游离乙烯攻击金属中心并形成五坐标双（乙烯）过渡态而发生的。该过程的活化自由能为<43 kJ mol –1对于未受阻的吡啶，> 76 kJ mol –1；对于在邻位有两个甲基取代基的吡啶，> 76 kJ mol –1。

DOI：

10.1039/dt9770000651
作为产物：

描述：

potassium tetrachloroplatinate(II) 在盐酸、乙烯作用下，以 not given 为溶剂，生成无水蔡斯盐

参考文献：

名称：

铂（II）配合物的反应。第2部分。三氯（η-乙烯）铂（II）（Zeise阴离子）催化四氯铂（II）离子的水合反应

摘要：

[PtCl 4 ] 2 + + H 2 O → [PtCl 3（OH 2）] – + Cl –在[PtCl 3（C 2 H 4）] –存在下反应进行得更快，尽管该作用趋于消失。通过增加氯离子的浓度逐渐增加。实际的催化剂被认为是反式-[PtCl 2（C 2 H 4）（OH 2）]，因为速率的增加与该络合物的浓度成正比。

DOI：

10.1039/dt9780000158
作为试剂：

描述：

1,1,3,3-四甲基二硅氧烷、苯乙酮在 chloro(1,5-cyclooctadiene)rhodium(I) dimer 无水蔡斯盐作用下，生成 1,1,3,3-tetramethyl-1-(1-phenylethoxy)disiloxane

参考文献：

名称：

Asymmetrische Katalysen, 39. Mitt.: Monohydrosilane in der enantioselektiven katalytischen Hydrosilylierung prochiraler Ketone

摘要：

DOI：

10.1007/bf00809204

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文献信息

Platinum(II) and palladium(II) complexes of thiacyclooct-4-enes; an unusual metal-catalyzed olefin isomerization

作者：Luigi Busetto

DOI：10.1016/s0022-328x(00)82421-3

日期：1980.3

Reaction of CN− with the adduct obtained from PtCl42− and a mixture of cis- and trans-2-methylthiacyclooct-4-ene liberates the cis ligand, and GLC analysis excludes the presence of free trans olefin. It is suggested that platinum complexes induce extensive trans→cis olefin isomerization.

的MCL反应4 2- （M =钯，铂）与顺-thiacyclooct -4-烯，顺式-2- methylthiacyclooct -4-烯和顺-2- phenylthiacyclooct -4-烯（顺-S -4-辛）得到通式MCl 2（顺式-S -4-辛基）的螯合物。X射线结构测定表明与金属的配位同时通过烯烃双键和硫原子发生。CN的反应-与氯铂酸得到的加合物4 2-和的混合物的顺式-和反式-2- methylthiacyclooct -4-烯释放出顺配体，GLC分析排除了游离反式烯烃的存在。建议铂络合物诱导广泛的反式→顺式烯烃异构化。
Synthesis and reactivity of cis-dichloro(enamine)(amine)platinum(II) complexes

作者：Sheryl L. Doran、David B. Brown、Christopher W. Allen

DOI：10.1016/0022-328x(88)80558-8

日期：1988.2

The reaction of Zeise's dimer, trans-μ-dichlorobis(ethylene)platinum(II) chloride, with a variety of alkyl-substituted enamines led to complexes of the type cis-[Pt(C(2)-enamine)(amine)Cl2], where the enamine ligand is coordinated to the platinum(II) center through its nucleophilic carbon atom (C(2)) and the amine ligand is derived from the parent enamine. Analogous palladium complexes were prepared

Zeise的二聚体反式-μ-二氯双（乙烯）铂（II）与各种烷基取代的烯胺的反应导致顺式-[Pt（C（2）-enamine）（amine）Cl 2 ]，其中烯胺配体通过其亲核碳原子（C（2））与铂（II）中心配位，并且胺配体衍生自母体烯胺。制备了类似的钯配合物。通过元素分析，NMR（1 H，13 C）和IR光谱对复合物进行表征。
Nucleophilic attack on olefins co-ordinated to platinum. Part 2. Stabilities of 2-ammonioethanide ? adducts and of five-co-ordinate complexes

作者：Ibrahim M. Al-Najjar、Michael Green

DOI：10.1039/dt9790001651

日期：——

+ PtII(η-C2H4)⇌σ-amCH2H2Pt, and are discussed in terms of the nature of am, the attacking amine. Lack of bulk in am is more important than its basicity, π effects also being relevant. Data are also given on an equilibrium in which five-co-ordinate complexes are produced, e.g. py +[PtCl2(η-C2H4)(py)]⇌[PtCl2(η-C2H4)(py)2](py = pyridine). The reaction is specific to aromatic amines, which suggests that

报道了各种新的2-氨碘乙烷-铂（II）配合物（即含有amCH 2 H 2 Pt，am =胺的化合物）的制备和表征。这些已用于通过1 H nmr光谱法鉴定其他较不稳定的亲戚。nmr数据未显示复合物的稳定性。已经研究了amCH 2 H 2基团的反式标签化；在nmr时间尺度上，转位胺的交换是缓慢的。平衡常数已经测量为反应上午+铂II（η-C 2 H ^ 4）⇌ σ-amCH 2 ħ 2 Pt和在上午的性质，攻击胺来讨论。am缺乏体积比其基本性更为重要，π效应也很重要。数据被在其中五坐标复合物所产生的平衡，也给出了例如PY + [氯铂酸2（η-C 2 H ^ 4）（PY）] ⇌ [氯铂酸2（η-C 2 H ^ 4）（PY ）2 ]（py =吡啶）。该反应特定于芳族胺，这表明π相互作用在缔合取代中很重要。η-C的易感性2 ħ 4和Pt将II对亲核攻击进行比较，前者是较硬的酸。
Reversible multi-electron storage in dual-site redox-active supramolecular cages

作者：Raoul Plessius、Nicole Orth、Ivana Ivanović-Burmazović、Maxime A. Siegler、Joost N. H. Reek、Jarl Ivar van der Vlugt

DOI：10.1039/c9cc07138e

日期：——

M6L412+ supramolecular cages 3a and 3b (M = Pd, Pt), soluble in organic solvents, contain two different ligand-centered redox sites that enable the reversible storage of up to 16 electrons, as probed by CV, UV/vis spectro-electrochemistry (SEC-UV/Vis), bulk electrolysis and EPR. Encapsulation of a B12F122− anion is confirmed by 1H, 19F NMR and 19F DOSY NMR spectroscopy and mass spectrometry.

可溶于有机溶剂的M 6 L 4 12+超分子笼3a和3b（M = Pd，Pt）包含两个不同的以配体为中心的氧化还原位点，通过CV，UV /可见光谱电化学（SEC-UV / Vis），本体电解和EPR。B 12 F 12 2-阴离子的包封通过1 H，19 F NMR和19 F DOSY NMR光谱学和质谱法确定。
Complexation d'iminopyridines par le sel de zeise: voie d'access a des conjugues estradiol-cis-dichloro platine. Etude structure du complexe cis-PtCl2[C5H4NCH2NC(CH3)C6H4OH],H2O

作者：Philippe Pointeau、Henri Patin、Abdelhamid Mousser、Jean-Yves Le Marouille

DOI：10.1016/0022-328x(86)80303-5

日期：1986.9

and characterized. The (2-pyridyl)CHNR1 and (2-pyridyl)CH2NCR1R2 ligands react with Zeise's salt to afford directly the pentagonal chelates PtCl2L. Their structure and the cis-stereo-chemistry were shown by the usual spectroscopic methods and for cis-PtCl2[C5H4NCH2NC(CH3)C6H4OH],H2O by an X-ray diffraction study. On the other hand, the (2-pyridyl)(CH2)2NCR1R2 ligands do not afford the expected hexagonal

为了合成五和六边形的铂（II）金属环，已制备并表征了二齿配体，例如亚氨基吡啶（L）。的（2-吡啶基）CHNR 1和（2-吡啶基）CH 2 NCR 1 - [R 2个配体与蔡斯盐直接得到五边形螯合物氯铂酸反应2 L.它们的结构和顺-stereo-化学均表现通过常规的光谱方法和用于顺-PtCl 2 [C 5 H ^ 4 NCH 2 NC（CH 3）C 6 H ^ 4 OH]，H 2通过X射线衍射研究O。另一方面，（2-吡啶基）（CH 2）2 N ＝ CR 1 R 2配体不能提供预期的六角形金属环。相反，在亚胺的氮原子处络合后，它们会生成配位体水解后形成的（2-吡啶基）乙胺络合物。配合物的反式- [乙烯] - [（2-吡啶基）（CH 2）2 NCR 1 - [R 2 ]氯铂酸2表示当R 1是雌二醇“细胞毒性具有延迟活性”的模型。

无水蔡斯盐 | 12012-50-9

分子结构分类

物化性质

计算性质

安全信息

SDS

反应信息

文献信息

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