6-[tris(trimethylsilyl)]-3-octanol | 1001067-37-3

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 6-[tris(trimethylsilyl)]-3-octanol
• 英文别名: 1-Tris(trimethylsilyl)silyloctan-3-ol；1-tris(trimethylsilyl)silyloctan-3-ol
• CAS: 1001067-37-3
• 化学式: C₁₇H₄₄OSi₄
• 分子量: 376.878
• InChiKey: WWOGRCOJMJTMBR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.02
• 重原子数：
  22
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-辛烯-3-醇 、 三(三甲基硅基)硅烷 在 1,1'-偶氮(氰基环己烷) 作用下， 以 水 为溶剂， 反应 4.0h， 以99%的产率得到6-[tris(trimethylsilyl)]-3-octanol
  参考文献：
  名称：

  Radical Reactions in Aqueous Medium Using (Me₃Si)₃SiH

  摘要：

  (Me3Si)(3)SiH was used as a successful reagent in a variety of radical-based transformations in water. The system comprising substrate, silane, and initiator (ACCN) mixed in aqueous medium at 100 degrees C worked well for both hydrophilic and hydrophobic substrates, with the only variation that an amphiphilic thiol was also needed in case of the water-soluble compounds.

  DOI：

  10.1021/ol7020803

文献信息

• Radical Reactions in Aqueous Medium Using (Me₃Si)₃SiH
  作者：Al Postigo、Sergey Kopsov、Carla Ferreri、Chryssostomos Chatgilialoglu

  DOI：10.1021/ol7020803

  日期：2007.12.1

  (Me3Si)(3)SiH was used as a successful reagent in a variety of radical-based transformations in water. The system comprising substrate, silane, and initiator (ACCN) mixed in aqueous medium at 100 degrees C worked well for both hydrophilic and hydrophobic substrates, with the only variation that an amphiphilic thiol was also needed in case of the water-soluble compounds.