1,2-bis(cyclohexylphosphino)ethane | 18899-63-3

• 分子结构分类: 有机化合物 - 有机磷化合物
• 英文名称: 1,2-bis(cyclohexylphosphino)ethane
• 英文别名: 1,2-dicyclohexylphosphinoethane；dcpe；Ethylen-bis-cyclohexylphosphin；Ethylen-1,2-bis-monocyclohexylphosphin；cyclohexyl(2-cyclohexylphosphanylethyl)phosphane
• CAS: 18899-63-3
• 化学式: C₁₄H₂₈P₂
• 分子量: 258.324
• InChiKey: JYBWGIWGBANSPY-UHFFFAOYSA-N

物化性质

• 沸点：
  162-168 °C(Press: 4 Torr)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,2-bis(cyclohexylphosphino)ethane 在 sodium peroxide 作用下， 生成 Ethylen-bis-cyclohexylphosphinsaeure
  参考文献：
  名称：

  Issleib,K.; Weichmann,H., Chemische Berichte, 1968, vol. 101, # 6, p. 2197 - 2202

  摘要：

  DOI：
• 作为产物：
  描述：

  Ethylen-bis-(cyclohexylphosphinsaeure-isopropylester) 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 生成 1,2-bis(cyclohexylphosphino)ethane
  参考文献：
  名称：

  Issleib,K.; Weichmann,H., Chemische Berichte, 1968, vol. 101, # 6, p. 2197 - 2202

  摘要：

  DOI：

文献信息

• Rhodium nitrosyl catalysts for CO₂ hydrogenation to formic acid under mild conditions
  作者：Fenglou Zou、Jacqueline M. Cole、Timothy G. J. Jones、Li Jiang

  DOI：10.1002/aoc.2898

  日期：2012.10

  A new synthetic protocol for catalysing CO2 hydrogenation to formic acid under mild conditions is reported, and the CO2 hydrogenation is efficiently achieved by dcpe‐rhodium‐nitrosyl catalyst precursors, Rh(NO)(dcpe) (1) (dcpe = 1,2‐dicyclohexylphosphinoethane) and Rh(III)(NO)(dcpe)Cl2 (2). The catalytic activity of 1 is noteworthy for being able to proceed in the absence of protic conditions. Compound

  用于催化CO的新合成协议2温和的条件下氢化，以甲酸报道，和CO 2加氢有效地通过DCPE -铑-亚硝酰基的催化剂前体来实现，铑（NO）（DCPE）（1）（DCPE = 1， 2-二环己基次膦酸酯）和Rh（III）（NO）（dcpe）Cl 2（2）。1的催化活性值得注意，因为它可以在没有质子条件的情况下进行。化合物2的特征在于NMR，IR和X射线晶体学。特别是，观察到2带有一个弯曲的NO配体，其Rh–N–O角为115.7（3）°，代表已知的最小M–N–O角之一。版权所有©2012 John Wiley＆Sons，Ltd.
• COPPER CATALYZED HALOGENATON AND REACTION PRODUCTS
  申请人：Wisconsin Alumni Research Foundation

  公开号：US20140371480A1

  公开（公告）日：2014-12-18

  A Cu(I)-catalyzed 1,3-halogen migration reaction effectively recycles an activating group by transferring a halogen from an sp 2 to a benzylic carbon with good enantioselectivity and concomitant borylation of the Ar-halo bond. The resulting enantio-enriched benzyl halide can be reacted in the same vessel under a variety of conditions to form an additional carbon-heteroatom or carbon-carbon bond while maintaining high ee. The reaction can be used to efficiently prepare novel compounds and intermediates for the preparation of therapeutics and ligands for catalysis.

  一种Cu(I)催化的1,3-卤迁移反应有效地通过将卤素从sp2转移到苄基碳来循环利用一个活化基团，具有良好的对映选择性并伴随Ar-卤键的硼化反应。所得的对映富集的苄基卤化物可以在同一容器中在各种条件下反应，形成额外的碳-杂原子或碳-碳键，同时保持高的ee。该反应可用于高效制备新型化合物和制备治疗剂和催化剂配体的中间体。
• Structural exploration of rhodium catalysts and their kinetic studies for efficient parahydrogen-induced polarization by side arm hydrogenation
  作者：Marino Itoda、Yuki Naganawa、Makoto Ito、Hiroshi Nonaka、Shinsuke Sando

  DOI：10.1039/c9ra02580d

  日期：——

  technique using transition metal-catalysed hydrogenation with parahydrogen. We examined rhodium catalysts and their kinetic studies, rarely considered in the research of current PHIP. It emerged that rhodium complexes with electron-donating bisphosphine ligands, with a dicyclohexylphosphino group, appear to be more effective than conventional rhodium catalysts.

  仲氢诱导极化 (PHIP) 是一种使用过渡金属催化的仲氢加氢的快速且具有成本效益的超极化技术。我们检查了铑催化剂及其动力学研究，在当前的 PHIP 研究中很少考虑。结果表明，具有二环己基膦基的给电子双膦配体的铑络合物似乎比传统的铑催化剂更有效。
• BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX
  申请人：Asaumi Taku

  公开号：US20100184978A1

  公开（公告）日：2010-07-22

  A bipyridine compound represented by the formula (1): wherein R 1 , R 2 and R 3 each independently represent a C1-C10 alkyl group which may be substituted etc., and R 4 , R 5 , R 6 , R 7 and R 8 each independently represent a hydrogen atom etc., a transition metal complex obtained by contacting a bipyridine compound represented by the formula (1) with a compound of a transition metal belonging to Group 9, 10 or 11, and a method for production of a conjugated aromatic compound comprising reacting an aromatic compound (A) wherein one or two leaving groups are bonded to an aromatic ring with an aromatic compound (A) having the same structure as that of the above-mentioned aromatic compound (A) or an aromatic compound (B) being structurally different from the above-mentioned aromatic compound (A) and having one or two leaving groups bonded to an aromatic ring, in the presence of the transition metal complex.

  一种以式(1)表示的联吡啶化合物：其中R1、R2和R3各自独立地表示可以被取代的C1-C10烷基等，而R4、R5、R6、R7和R8各自独立地表示氢原子等，通过将式(1)表示的联吡啶化合物与属于9、10或11族过渡金属的化合物接触而获得的过渡金属配合物，以及一种制备共轭芳香化合物的方法，包括在过渡金属配合物的存在下，将一个或两个离去基团与芳环结合的芳香化合物（A）与具有与上述芳香化合物（A）相同结构的芳香化合物（A）或结构不同于上述芳香化合物（A）且具有一个或两个离去基团与芳环结合的芳香化合物（B）反应。
• TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX
  申请人：Asaumi Taku

  公开号：US20110046336A1

  公开（公告）日：2011-02-24

  A transition metal complex obtained by contacting a bipyridine compound represented by the formula (1): wherein R 1 , R 2 and R 3 represent a C1-C10 alkyl group which may be substituted, etc., and R 4 and R 5 represent a hydrogen atom etc., with a compound of a transition metal belonging to Group 9, 10 or 11, and a process for producing a conjugated aromatic compound comprising reacting an aromatic compound (A) wherein one or two leaving groups are bonded to an aromatic ring with an aromatic compound (A) having the same structure as that of the above-mentioned aromatic compound (A) or an aromatic compound (B) being structurally different from the above-mentioned aromatic compound (A) and having one or two leaving groups bonded to an aromatic ring, in the presence of said transition metal complex.

  通过将式（1）所表示的联吡啶化合物与属于9、10或11族的过渡金属化合物接触而获得的过渡金属配合物，其中R1、R2和R3代表C1-C10烷基，可以被取代等，而R4和R5代表氢原子等。制备共轭芳香化合物的方法包括，在所述过渡金属配合物的存在下，将一个芳香化合物（A），其中一个或两个离去基团与芳香环相键合，与具有与上述芳香化合物（A）相同结构的芳香化合物（A）或在结构上不同于上述芳香化合物（A）并且具有一个或两个离去基团与芳香环相键合的芳香化合物（B）反应。