3-hydroxy-8-methyl-nortropane-3-carbonitrile | 40131-43-9

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 托烷生物碱
• 英文名称: 3-hydroxy-8-methyl-nortropane-3-carbonitrile
• 英文别名: 3-hydroxy-tropane-3-carbonitrile；3-Hydroxy-tropan-3-carbonitril；3-Hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-3-carbonitrile
• CAS: 40131-43-9
• 化学式: C₉H₁₄N₂O
• 分子量: 166.223
• InChiKey: WSYMOTWLPRNFID-UHFFFAOYSA-N

物化性质

• 沸点：
  334.9±42.0 °C(Predicted)
• 密度：
  1.19±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  47.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  盐酸 、 3-hydroxy-8-methyl-nortropane-3-carbonitrile 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Willstaetter, Chemische Berichte, 1896, vol. 29, p. 2218,2220

  摘要：

  DOI：
• 作为产物：
  描述：

  氰化钾 、 alkaline earth salt of/the/ methylsulfuric acid 生成 3-hydroxy-8-methyl-nortropane-3-carbonitrile
  参考文献：
  名称：

  Macrophage intracellular signaling induced by Listeria monocytogenes

  摘要：

  Macrophages are critical for control of Listeria monocytogenes infections; accordingly, the interactions of L. monocytogenes with these cells have been intensively studied. It has become apparent that this facultative intracellular pathogen interacts with macrophages both prior to entry and during the intracellular phase. This review covers recent work on signaling induced in macrophages by L. monocytogenes, especially intracellular signals induced by secreted proteins including listeriolysin O and two distinct phospholipases C. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

  DOI：

  10.1016/s1286-4579(02)00011-4

文献信息

• DE91711
  申请人：——

  公开号：——

  公开（公告）日：——
• Macrophage intracellular signaling induced by Listeria monocytogenes
  作者：Howard Goldfine、Sandra J. Wadsworth

  DOI：10.1016/s1286-4579(02)00011-4

  日期：2002.11

  Macrophages are critical for control of Listeria monocytogenes infections; accordingly, the interactions of L. monocytogenes with these cells have been intensively studied. It has become apparent that this facultative intracellular pathogen interacts with macrophages both prior to entry and during the intracellular phase. This review covers recent work on signaling induced in macrophages by L. monocytogenes, especially intracellular signals induced by secreted proteins including listeriolysin O and two distinct phospholipases C. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
• Willstaetter, Chemische Berichte, 1896, vol. 29, p. 2218,2220
  作者：Willstaetter

  DOI：——

  日期：——