dipotassium acetylide | 22754-96-7

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: dipotassium acetylide
• 英文别名: Kaliumcarbid
• CAS: 22754-96-7
• 化学式: C₂K₂
• 分子量: 102.219
• InChiKey: LBYLKELJGGGBMJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.76
• 重原子数：
  4.0
• 可旋转键数：
  0.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  (8S,9R,13S,14S)-9-hydroxy-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione 、 dipotassium acetylide 生成 4-methyl-17α-ethynyl-17β-hydroxy-19-norandrosta-4,9-diene-1-one
  参考文献：
  名称：

  KAPUR, JAGDISH C.;MARX, ARTHUR F.;VERWEIJ, JAN, STEROIDS, 52,(1988) N, C. 181-186

  摘要：

  DOI：

文献信息

• The chemistry of 9α-hydroxysteroids. 1. preparation of 9α,17β-dihydroxy-17α-ethynylandrost-4-en-3-one
  作者：Jagdish C. Kapur、Arthur F. Marx、Jan Verweij

  DOI：10.1016/0039-128x(88)90002-5

  日期：1988.9

  9 alpha-Hydroxyandrost-4-ene-3,17-dione 1, when allowed to react with dipotassium acetylide in tetrahydrofuran, resulted, after chromatographic separation, in 4-methyl-19-norandrosta-4,9-diene-1,17-dione 2, 4 xi-methyl-19-norandrosta-5(10),9(11)-diene-1,17-dione 3, 4-methyl-17 alpha-ethynyl-17 beta-hydroxy-19-norandrosta-4,9-dien-1-one 4, 4 xi-methyl-17 alpha-ethynyl-17 beta-hydroxy-19-norandrosta-5(10),9(11)-dien- 1-one 5, and 17 alpha-ethynyl-17 beta-hydroxy-9,10-secoandrost-4-ene-3,9-dione 6. Selective protection of delta 4-3-ketone of 9 alpha-hydroxyandrost-4-ene-3,17-dione 1 as its dienol methyl ether 7, and subsequent reaction with lithium acetylide-ethylenediamine followed by acidic hydrolysis, afforded 9 alpha,17 beta-dihydroxy-17 alpha- ethynylandrost-4-en-3-one 8.
• KAPUR, JAGDISH C.;MARX, ARTHUR F.;VERWEIJ, JAN, STEROIDS, 52,(1988) N, C. 181-186
  作者：KAPUR, JAGDISH C.、MARX, ARTHUR F.、VERWEIJ, JAN

  DOI：——

  日期：——