Butanoic acid, 4-[bis(4-methoxyphenyl)phenylmethoxy]- | 150907-74-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: Butanoic acid, 4-[bis(4-methoxyphenyl)phenylmethoxy]-
• 英文别名: 4-[bis(4-methoxyphenyl)-phenylmethoxy]butanoic acid
• CAS: 150907-74-7
• 化学式: C₂₅H₂₆O₅
• 分子量: 406.5
• InChiKey: ULVZSABKUFQJDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  30
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  65
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Polyalkyleneamine-containing oligomers
  申请人：——

  公开号：US20040019000A1

  公开（公告）日：2004-01-29

  The present invention relates to novel polyethylenamine-conjugated oligomeric compounds and to methods of making such compounds. The invention further relates to methods of enhancing the cellular uptake of oligomeric compounds comprising conjugating the compounds to fusogenic moieties such as polyethylenimine.

  本发明涉及新型聚乙烯胺共轭寡聚合物化合物以及制备这种化合物的方法。该发明进一步涉及通过将这些化合物共轭到融合素基团（如聚乙烯亚胺）来增强寡聚合物化合物的细胞摄取方法。
• Process for preparing peptide derivatized oligomeric compounds
  申请人：——

  公开号：US20020156235A1

  公开（公告）日：2002-10-24

  Methods of preparing peptide linked oligomeric compounds are provided. The method is useful for preparing larger scale amounts of peptide linked oligomeric compounds. More particularly, the synthesis of peptide linked oligomeric compounds is performed without the problems of aggregation associated with electrostatic interactions. The present method describes using equimolar amounts of oligomeric compounds and peptide reagents providing for an increase in overall efficiency.

  提供了制备肽链寡聚化合物的方法。该方法适用于制备规模较大的肽链寡聚化合物。更具体地说，肽链寡聚化合物的合成是在没有与静电相互作用有关的聚集问题的情况下进行的。本方法描述了使用等摩尔量的寡聚化合物和肽试剂，从而提高了整体效率。
• US6559279B1
  申请人：——

  公开号：US6559279B1

  公开（公告）日：2003-05-06
• US6762281B2
  申请人：——

  公开号：US6762281B2

  公开（公告）日：2004-07-13
• [EN] PROCESS FOR PREPARING PEPTIDE DERIVATIZED OLIGOMERIC COMPOUNDS<br/>[FR] PROCÉDÉ POUR L'ÉLABORATION DE COMPOSÉS OLIGOMÈRES EN DÉRIVATION DE PEPTIDES
  申请人：ISIS PHARMACEUTICALS INC

  公开号：WO2002020544A1

  公开（公告）日：2002-03-14

  Methods of preparing peptide linked oligomeric compounds are provided. The method is useful for preparing larger scale amounts of peptide linked oligomeric compounds. More particularly, the synthesis of peptide linked oligomeric compounds is performed without the problems of aggregation associated with electrostatic interactions. The present method describes using equimolar amounts of oligomeric compounds and peptide reagents providing for an increase in overall efficiency.