((E)-2-Methoxy-2-trimethylsilanyloxy-vinyl)-dimethyl-amine | 169260-02-0

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: ((E)-2-Methoxy-2-trimethylsilanyloxy-vinyl)-dimethyl-amine
• 英文别名: 2-Methoxy-N,N-dimethyl-2-[(trimethylsilyl)oxy]ethen-1-amine；2-methoxy-N,N-dimethyl-2-trimethylsilyloxyethenamine
• CAS: 169260-02-0
• 化学式: C₈H₁₉NO₂Si
• 分子量: 189.33
• InChiKey: OPHIHGNVZSQGNO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.84
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  四氯化碳 、 ((E)-2-Methoxy-2-trimethylsilanyloxy-vinyl)-dimethyl-amine 反应 3.0h， 以57%的产率得到N,N-dimethyl-2-trichloromethylglycine methyl ester
  参考文献：
  名称：

  The reaction of ketene silyl acetals and silyl enol ethers with CCl4 without a promoter

  摘要：

  CCl 4 与烯酮甲硅烷基缩醛和甲硅烷基烯醇醚在不存在促进剂的情况下在环境温度或回流下或在光照射下进行反应，通过将三氯甲基加成到那些甲硅烷基底物上来形成产物。

  DOI：

  10.1039/a804028a

文献信息

• Reaction of Ketene Alkyl Trimethylsilyl Acetals with Dimethyl Acetylenedicarboxylate Catalyzed with Zirconium Tetrachloride
  作者：Michiharu Mitani、Takahiro Sudoh、Kikuhiko Koyama

  DOI：10.1246/bcsj.68.1683

  日期：1995.6

  acetylenedicarboxylate is reacted with ketene alkyl trimethylsilyl acetals in the presence of a catalytic amount of zirconium tetrachloride, dimethyl 2-alkoxycarbonyl-3-alkylidenebutanedioates are afforded. Although the silyl enol ether from acetophenone undergoes the same type of reaction, other trisubstituted silyl enol ethers such as those from butyrophenone and 3-pentanone fail to react with dimethyl

  当乙炔二羧酸二甲酯在催化量的四氯化锆存在下与乙烯酮烷基三甲基甲硅烷基缩醛反应时，得到2-烷氧基羰基-3-亚烷基丁二酸二甲酯。尽管来自苯乙酮的甲硅烷基烯醇醚经历了相同类型的反应，但其他三取代的甲硅烷基烯醇醚如来自丁苯酮和3-戊酮的那些在这些条件下不能与乙炔二羧酸二甲酯反应。
• The reaction of ketene silyl acetals and silyl enol ethers with CCl4 without a promoter
  作者：Michiharu Mitani、Hideo Sakata

  DOI：10.1039/a804028a

  日期：——

  The reaction of CCl4 with ketene silyl acetals and silyl enol ethers in the absence of a promoter at ambient temperature or at reflux, or under photo-irradiation, was performed to form products via addition of the trichloromethyl group to those silyl substrates.

  CCl 4 与烯酮甲硅烷基缩醛和甲硅烷基烯醇醚在不存在促进剂的情况下在环境温度或回流下或在光照射下进行反应，通过将三氯甲基加成到那些甲硅烷基底物上来形成产物。
• Addition Reactions of Polyhalides to Ketene Silyl Acetals and Silyl Enol Ethers under Thermal or Photo-Irradiated Conditions without a Promoter
  作者：Michiharu Mitani、Hideo Sakata、Hisayuki Tabei

  DOI：10.1246/bcsj.75.1807

  日期：2002.8

  The reactions of ketene silyl acetals and silyl enol ethers in a CCl4 solution containing no promoter under ambient temperature, reflux, or photo-irradiation conditions afforded products via the addition of a trichloromethyl group to those silyl substrates. Polyhalides other than CCl4 were subjected to photoreactions in a hexane solution, resulting in the formation of carbonyl derivatives based on

  乙烯酮甲硅烷基缩醛和甲硅烷基烯醇醚在不含促进剂的 CCl4 溶液中在环境温度、回流或光照射条件下反应，通过向这些甲硅烷基底物添加三氯甲基提供产物。除 CCl4 外的多卤化物在己烷溶液中进行光反应，导致基于多卤代烷基加成的羰基衍生物的形成。