Ethylen-bis-(trimethylphosphonium)-Ion | 26802-56-2

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: Ethylen-bis-(trimethylphosphonium)-Ion
• 英文别名: hexa-P-methyl-P,P'-ethanediyl-di-phosphonium; dibromide；Hexa-P-methyl-P,P'-aethandiyl-di-phosphonium; Dibromid；Hexa-P-methyl-P,P'-aethandiyl-di-phosphonium; Aethylen-bis-trimethylphosphoniumdibromid
• CAS: 26802-56-2
• 化学式: 2Br*C₈H₂₂P₂
• 分子量: 340.018
• InChiKey: BMGCQTBGSFKXKL-UHFFFAOYSA-M

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氢氧化钾 作用下， 生成 Ethylen-bis-(trimethylphosphonium)-Ion
  参考文献：
  名称：

  Renshaw; Bishop, Journal of the American Chemical Society, 1938, vol. 60, p. 947

  摘要：

  DOI：

文献信息

• Phosphocholine 2, 6-xylyl ether bromide: proton-phosphorus coupling constants and preliminary pharmacological assessment
  作者：E R Clark、I E Hughes

  DOI：10.1111/j.2042-7158.1970.tb08519.x

  日期：2011.4.12

  Phosphocholine 2, 6-xylyl ether bromide [PPP-trimethyl-2-(2, 6-xylyloxy)ethylphosphonium bromide], has been synthesized by reacting 2-(2, 6-xylyloxy)ethyl bromide with a solution of trimethyl-phosphine in phenol, but ethylenebis(trimethylphosphonium bromide), 1, 2-di(2, 6-xylyloxy)ethane and 2, 6-xylenol were the only reaction products identified when ether was used as solvent. The 2JPH and 3JPH coupling constants for these phosphonium salts have been determined. Although the phosphocholine xylyl ether blocks the Finkleman preparation in concentrations of 2–3 × 10−5 g/ml, this blockade does not have all the characteristics of the adrenergic neuron blockade produced by xylocholine.

  通过将2-(2,6-二甲氧基苯氧基)乙基溴与苯酚中的三甲基膦溶液反应，合成了磷酸胆碱2,6-二甲氧基苯醚溴化物[PPP-三甲基-2-(2,6-二甲氧基苯氧基)乙基磷酸胆碱溴化物]，但当以醚作为溶剂时，乙二醇二(三甲基溴化磷)酸酯、1,2-二(2,6-二甲氧基苯氧基)乙烷和2,6-二甲苯酚是唯一确定的反应产物。已确定了这些磷酸胆碱盐的2JPH和3JPH耦合常数。虽然磷酸胆碱二甲氧基苯醚在2-3×10-5 g/ml的浓度下阻断了Finkleman制剂，但这种阻断并没有所有由xylocholine产生的肾上腺素能神经元阻断的特征。

• Hofmann,A.W., Justus Liebigs Annalen der Chemie, 1861, vol. Suppl.1, p. 287
  作者：Hofmann,A.W.

  DOI：——

  日期：——