(E)-1,2-bis(3-ethynylphenyl)diazene | 1373930-59-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: (E)-1,2-bis(3-ethynylphenyl)diazene
• CAS: 1373930-59-6
• 化学式: C₁₆H₁₀N₂
• 分子量: 230.269
• InChiKey: OGCXMEOHXWCKMM-ISLYRVAYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.06
• 重原子数：
  18.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  24.72
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  (E)-1,2-bis(3-ethynylphenyl)diazene 、 2,5-bis(dodecyloxy)-4-iodobenzaldehyde 在 bis-triphenylphosphine-palladium(II) chloride 、 copper(l) iodide 作用下， 以 四氢呋喃 、 二异丙胺 为溶剂， 以60%的产率得到(E)-4,4'-((diazene-1,2-diylbis(3,1-phenylene))bis(ethyne-2,1-diyl))bis(2,5-bis(dodecyloxy)benzaldehyde)
  参考文献：
  名称：

  Light-Induced Ostwald Ripening of Organic Nanodots to Rods

  摘要：

  Ostwald ripening allows the synthesis of 1D nanorods of metal and semiconductor nanoparticles. However, this phenomenon is unsuccessful with organic it-systems due to their spontaneous self-assembly to elongated fibers or tapes. Here we demonstrate the uses of light as a versatile tool to control the ripening of amorphous organic nanodots (ca. 15 nm) of an azobenzene-derived molecular assembly to micrometer sized supramolecular rods. A surface confined dipole variation associated with a low-yield (13-14%) trans-cis isomerization of the azobenzene moiety and the consequent dipole-dipole interaction in a nonpolar solvent is believed to be the driving force for the ripening of the nanodots to rods.

  DOI：

  10.1021/ja301002g

文献信息

• Copper Nitrate Mediated Regioselective [2+2+1] Cyclization of Alkynes with Alkenes: A Cascade Approach to Δ²-Isoxazolines
  作者：Mingchun Gao、Yingying Li、Yuansheng Gan、Bin Xu

  DOI：10.1002/anie.201503393

  日期：2015.7.20

  An efficient method for the regioselective synthesis of pharmacologically relevant polysubstituted Δ2‐isoxazolines is based on the copper‐mediated direct transformation of simple terminal alkynes and alkenes. The overall process involves the formation of four chemical bonds with inexpensive and readily available copper nitrate trihydrate as a novel precursor of nitrile oxides. The reaction can be easily

  对于药理学相关多取代Δ的区域选择性合成的有效方法2个-isoxazolines基于简单末端炔烃和烯烃的铜介导的直接转化。整个过程涉及与廉价且容易获得的三水合硝酸铜作为腈氧化物的新型前体形成四个化学键。该反应可以容易地进行，并且可以在温和的条件下进行。