CDD 3522 | 35629-11-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: CDD 3522
• 英文别名: 1-(o-Tolyl-diphenylmethyl)-imidazol；1-(2-methyl-trityl)-1H-imidazole；1-[(2-Methylphenyl)-diphenylmethyl]imidazole
• CAS: 35629-11-9
• 化学式: C₂₃H₂₀N₂
• 分子量: 324.425
• InChiKey: RWRJOCALJRQEQQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• METHOD FOR ASSESSING ABSORPTION PROPERTIES OF LOW SOLUBILITY COMPOUNDS
  申请人：F. Hoffmann-La Roche AG

  公开号：EP1991864B1

  公开（公告）日：2018-03-21
• NOVEL 2 -IMIDAZOLES AS LIGANDS FOR TRACE AMINE ASSOCIATED RECEPTORS (TAAR)
  申请人：F. Hoffmann-La Roche AG

  公开号：EP2101762A1

  公开（公告）日：2009-09-23
• LOCAL TREATMENT OF NEUROFIBROMAS
  申请人：OncoSynergy, Inc.

  公开号：US20150182452A1

  公开（公告）日：2015-07-02

  A method for treating a neurofibroma, e.g. dermal neurofibroma, a subdermal neurofibroma, or a superficial plexiform neurofibroma, in a subject in need of such treatment is disclosed. The method comprises locally applying a composition to a neurofibroma either topically or intralesionally. This method does not encompass systemic administration of the composition to the subject to have an effect on the neurofibromas. Compositions useful for such treatments and methods of preparing the compositions are disclosed.
• METHOD FOR TREATING INFLAMMATORY CONDITIONS
  申请人：NovelMed Therapeutics, Inc.

  公开号：US20150216876A1

  公开（公告）日：2015-08-06

  A method for treating an autoimmune disease in a subject includes administering to the subject a therapeutically effective amount of an agent comprising an imidazole, an estrogen receptor agonist, or pharmaceutically acceptable salts thereof.
• US9040507B2
  申请人：——

  公开号：US9040507B2

  公开（公告）日：2015-05-26