3,6-Diethyl-2,4-dioxo-1,2,3,4-tetrahydro-1,3,5-triazin | 69032-74-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 3,6-Diethyl-2,4-dioxo-1,2,3,4-tetrahydro-1,3,5-triazin
• 英文别名: 3,6-diethyl-1H-[1,3,5]triazine-2,4-dione；3,6-diethyl-1H-1,3,5-triazine-2,4-dione
• CAS: 69032-74-2
• 化学式: C₇H₁₁N₃O₂
• 分子量: 169.183
• InChiKey: OJOAJHJCDJKFRC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  61.8
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-(2,4-Diethylallophanoyl)-propionamidin 以70%的产率得到
  参考文献：
  名称：

  ETIENNE A.; LONCHAMBON G.; ROQUES J.; LEMMENS B.; PINTARD F., C. R. ACAD. SCI., 1978, C 287, NO 7, 285-288

  摘要：

  DOI：

文献信息

• PROKINETICIN 1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF PAIN
  申请人：Flores Christopher M.

  公开号：US20110319418A1

  公开（公告）日：2011-12-29

  Disclosed are compounds, compositions and methods for treating pain, including inflammatory, visceral, and acute pain. Such compounds are represented by Formula (I) as follows: wherein A 1 , L 1 , D, L 2 , and Q are defined herein.

  揭示了用于治疗疼痛的化合物、组合物和方法，包括炎症性、内脏性和急性疼痛。这些化合物由以下式（I）表示： 其中A1、L1、D、L2和Q在此处定义。
• Prokineticin 2 receptor antagonists
  申请人：Coats J. Steven

  公开号：US20080045535A1

  公开（公告）日：2008-02-21

  The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 2 or prokinetin 2 receptor mediated disorders.
• PROKINETICIN 1 RECEPTOR
  申请人：Mabus John R.

  公开号：US20110136811A1

  公开（公告）日：2011-06-09

  The present invention relates to methods of monitoring the biological activity of the PK1 receptor.
• PROKINETICIN 1 RECEPTOR ANTAGONISTS
  申请人：Coats Steven J.

  公开号：US20120129862A1

  公开（公告）日：2012-05-24

  The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 1 or prokinetin 1 receptor mediated disorders.
• US8188081B2
  申请人：——

  公开号：US8188081B2

  公开（公告）日：2012-05-29