(1-Chloro-propa-1,2-dienyl)-trimethyl-silane | 141642-52-6

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: (1-Chloro-propa-1,2-dienyl)-trimethyl-silane
• CAS: 141642-52-6
• 化学式: C₆H₁₁ClSi
• 分子量: 146.692
• InChiKey: KAAVMKKSQNPZEU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.77
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  1-chloro-2-(trimethylsilyl)cyclopropene 以60%的产率得到(1-Chloro-propa-1,2-dienyl)-trimethyl-silane
  参考文献：
  名称：

  The thermal rearrangements of halocyclopropenes

  摘要：

  The gas phase thermal chemistry of several halocyclopropenes has been investigated. In each instance the cyclopropene was converted cleanly to an allene.

  DOI：

  10.1016/s0040-4039(00)74152-9

文献信息

• Regioselective Allene Synthesis and Propargylations with Propargyl Diethanolamine Boronates
  作者：Daniel R. Fandrick、Jonathan T. Reeves、Zhulin Tan、Heewon Lee、Jinhua J. Song、Nathan K. Yee、Chris H. Senanayake

  DOI：10.1021/ol9022529

  日期：2009.12.3

  The utility of propargyl diethanolamine boronates as reagents for the preparation of allenes and homopropargylic alcohols is presented. Protonolysis with TFA and electrophilic substitution with N-halosuccinimides proceeded with inversion to provide the corresponding allene in high yield and regioselectivity. Alternatively, the propargylation of aldehydes was achieved with use of the in situ generated lithiated complex.