triethylammonium 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-α-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) | 1041747-55-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: triethylammonium 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-α-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate)
• CAS: 1041747-55-0
• 化学式: C₆H₁₅N*C₃₁H₆₁N₂O₁₅P
• 分子量: 833.995
• InChiKey: YYFRGKLEGIIYAH-PTYJHRSTSA-N

反应信息

• 作为产物：
  描述：

  triethylammonium 1-D-6-O-[2-(N-benzyloxyaminocarbonyl)amino-2-deoxy-3,4,6-tri-O-benzyl-α-D-glucopyranosyl]-2,3,4,5-tetra-O-benzyl-myo-inositol 1-(n-octadecyl phosphate) 在 palladium dihydroxide 氢气 作用下， 以 四氢呋喃 、 丙醇 为溶剂， 20.0 ℃ 、303.99 kPa 条件下， 反应 3.0h， 以94%的产率得到triethylammonium 1-D-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-α-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate)
  参考文献：
  名称：

  Synthesis of 1-d-6-O-[2-(N-hydroxyaminocarbonyl)amino-2-deoxy-α-d-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate): a potential metalloenzyme inhibitor of glycosylphosphatidylinositol biosynthesis

  摘要：

  1-D-6-O-[2-(N-Hydroxyaminocarbonyl)amino-2-deoxy-alpha-D-glucopyranosyl]-myo-inositol 1-(n-octadecyl phosphate) was prepared to probe the reaction mechanism of the putative zinc-dependent metalloenzyme 2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1-->6)-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2008.03.028