1,3-dibromo-1,3-dimethyl-1,3-diphenyldisiloxane | 333796-97-7

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 1,3-dibromo-1,3-dimethyl-1,3-diphenyldisiloxane
• 英文别名: Bromo-(bromo-methyl-phenylsilyl)oxy-methyl-phenylsilane
• CAS: 333796-97-7
• 化学式: C₁₄H₁₆Br₂OSi₂
• 分子量: 416.259
• InChiKey: YQWIQZDELLFJLP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.75
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,3-dibromo-1,3-dimethyl-1,3-diphenyldisiloxane 在 aq. NH₄Cl*NH₃ 作用下， 以 乙醚 为溶剂， 生成 meso-1,3-dimethyl-1,3-diphenyl-1,3-disiloxanediol 、 (S,S)-1,3-dimethyl-1,3-diphenyldisiloxane-1,3-diol
  参考文献：
  名称：

  A Stereoselective Approach to Optically Active Bifunctional 1,3-Dimethyl-1,3-diphenyldisiloxanes

  摘要：

  [GRAPHICS]Functionalized disiloxanes have attracted much attention as Versatile synthetic intermediates in the preparation of disiloxane containing polymers. In this report, a highly stereoselective (98% inversion) halogenating cleavage reaction of the silicon-naphthyl bond to obtain optically active (S,S)-1,3-dimethyl-1,3-diphenyldisiloxanediol ((S,S):(R,S):(R,R) = 86:14:0) was demonstrated.

  DOI：

  10.1021/ol990068n
• 作为产物：
  描述：

  (1S)-1-(4-methoxy-1-naphthyl)-1,3-dimethyl-3-(1-naphthyl)-1,3-diphenyldisiloxane 在 溴 作用下， 以 氯仿 为溶剂， 生成 1,3-dibromo-1,3-dimethyl-1,3-diphenyldisiloxane
  参考文献：
  名称：

  A Stereoselective Approach to Optically Active Bifunctional 1,3-Dimethyl-1,3-diphenyldisiloxanes

  摘要：

  [GRAPHICS]Functionalized disiloxanes have attracted much attention as Versatile synthetic intermediates in the preparation of disiloxane containing polymers. In this report, a highly stereoselective (98% inversion) halogenating cleavage reaction of the silicon-naphthyl bond to obtain optically active (S,S)-1,3-dimethyl-1,3-diphenyldisiloxanediol ((S,S):(R,S):(R,R) = 86:14:0) was demonstrated.

  DOI：

  10.1021/ol990068n