glycerophosphoglycerol | 185615-51-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: glycerophosphoglycerol
• 英文别名: Phosphatidylglycerol；Sn-glycero-3-phospho-(1'-sn-glycerol)；[(2S)-2,3-dihydroxypropyl] [(2R)-2,3-dihydroxypropyl] hydrogen phosphate
• CAS: 185615-51-4
• 化学式: C₆H₁₅O₈P
• 分子量: 246.154
• InChiKey: LLCSXHMJULHSJN-OLQVQODUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.6
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  137
• 氢给体数：
  5
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  glycerophosphoglycerol 、 2,2-二甲氧基-1,7,7-三甲基双环[2.2.1]庚烷 在 对甲苯磺酸 作用下， 以 乙腈 为溶剂， 生成
  参考文献：
  名称：

  A54145 Factor D Is Not Less Susceptible to Inhibition by Lung Surfactant than Daptomycin

  摘要：

  DOI：

  10.1021/acsinfecdis.2c00313

文献信息

• Use of a lipoteichoic acid, mono- or polyglycerophosphate for antibacterial pre-treatment and especially in medical devices
  申请人：Lunamed AG

  公开号：EP2574237A1

  公开（公告）日：2013-04-03

  The present invention refers to the use of a glycerophosphate derivative like lipoteichoic acid or mono- or polyglycerophosphate in antibacterial treatment of a surface or in antibacterially covering a surface, an antibacterial preparation preventing bacterial adhesion, a bacterially challenged surface or a medical device comprising at least one such lipoteichoic acid or mono- or polyglycerophosphate or its use in blocking adhesion sites of gram-positive bacteria.

  本发明指的是一种甘油磷酸酯衍生物（如硫代脂酸或单-或多-甘油磷酸酯）在表面抗菌处理或表面抗菌覆盖、防止细菌粘附的抗菌制剂、受细菌挑战的表面或医疗设备中的用途，这些表面或医疗设备至少包含一种这样的硫代脂酸或单-或多-甘油磷酸酯，或其在阻断革兰氏阳性细菌粘附点中的用途。
• [EN] COMPOSITIONS FOR DENTAL TREATMENT COMPRISING LIPOTEICHOIC ACIDS OR PARTS THEREOF LIKE MONO- OR POLYGLYCERPHOSPHATES<br/>[FR] COMPOSITIONS POUR LE TRAITEMENT DENTAIRE COMPRENANT DES ACIDES LIPOTÉICHOÏQUES OU DES PARTIES DE CEUX-CI TELS QUE DES MONO- OU DES POLYGLYCÉROPHOSPHATES
  申请人：LUNAMED AG

  公开号：WO2011120707A1

  公开（公告）日：2011-10-06

  The present invention refers to compositions for the treatment or prophylaxis of infectious or inflammatory processes in the oral cavity (cavitas oris) including dental hygiene, the composition comprising lipoteichoic acids and glycerophosphate derivatives, preferably added into a dental hygiene product like toothpastes, toothgels, creams or rinsing fluids, the use of glycerophosphate derivatives as prophylaxis against bacterial infections of the oral cavity like dental caries, or the use of poly-glycerophosphates for the production of a medicament for the treatment of or prophylaxis against bacterial infections of the oral cavity, like dental caries.