{(1R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-[(R)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-triethylsilanyloxy-hexa-1,5-diynyl]-1,5-bis-triethylsilanyloxy-cyclopent-2-enyl}-methanol | 189105-56-4

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: {(1R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-[(R)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-triethylsilanyloxy-hexa-1,5-diynyl]-1,5-bis-triethylsilanyloxy-cyclopent-2-enyl}-methanol
• CAS: 189105-56-4
• 化学式: C₄₁H₇₈O₇Si₄
• 分子量: 795.408
• InChiKey: HPIQETGDBYETDV-SZRLDXTHSA-N

反应信息

• 作为反应物：
  描述：

  {(1R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-[(R)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-triethylsilanyloxy-hexa-1,5-diynyl]-1,5-bis-triethylsilanyloxy-cyclopent-2-enyl}-methanol 在 戴斯-马丁氧化剂 作用下， 以 二氯甲烷 为溶剂， 以96%的产率得到(1S,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-[(R)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-triethylsilanyloxy-hexa-1,5-diynyl]-1,5-bis-triethylsilanyloxy-cyclopent-2-enecarbaldehyde
  参考文献：
  名称：

  Synthetic Study of Kedarcidin Chromophore: Advanced Models and Their Chemical Behavior

  摘要：

  The stereocontrolled synthesis of the appropriately functionalized ent-8,9-epoxybicyclo-[7.3.0]dodecadienediyne core 14 of kedarcidin chromophore 1 was achieved.

  DOI：

  10.1055/s-1997-780
• 作为产物：
  描述：

  2,2-Dimethyl-propionic acid (1R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-2-[(R)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-triethylsilanyloxy-hexa-1,5-diynyl]-1,5-bis-triethylsilanyloxy-cyclopent-2-enylmethyl ester 在 二异丁基氢化铝 作用下， 以 二氯甲烷 为溶剂， 以77%的产率得到{(1R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-2-[(R)-3-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-triethylsilanyloxy-hexa-1,5-diynyl]-1,5-bis-triethylsilanyloxy-cyclopent-2-enyl}-methanol
  参考文献：
  名称：

  Synthetic Study of Kedarcidin Chromophore: Advanced Models and Their Chemical Behavior

  摘要：

  The stereocontrolled synthesis of the appropriately functionalized ent-8,9-epoxybicyclo-[7.3.0]dodecadienediyne core 14 of kedarcidin chromophore 1 was achieved.

  DOI：

  10.1055/s-1997-780