5-Oxo-capronsaeure-thiophenylester | 91496-22-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚酯
• 英文名称: 5-Oxo-capronsaeure-thiophenylester
• 英文别名: S-phenyl 5-oxohexanethioate
• CAS: 91496-22-9
• 化学式: C₁₂H₁₄O₂S
• 分子量: 222.308
• InChiKey: JWFJWENMMBZKSI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  59.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-氧代己酸 、 苯硫酚 在 三氯氧磷 作用下， 生成 5-Oxo-capronsaeure-thiophenylester
  参考文献：
  名称：

  Wieland,T.; Staerk,J., Chemische Berichte, 1963, vol. 96, p. 2410 - 2419

  摘要：

  DOI：

文献信息

• Compounds For Specific Viral Target
  申请人：Bridon Dominique

  公开号：US20080039532A1

  公开（公告）日：2008-02-14

  The present application relates to a compound having a formula 1: B—R1-R2-M wherein B is a binding element for recognizing and binding a target; R1 is a first group of atoms for reacting with a functionality of the target so as to form a covalent bond with the target; R2 is a second group of atoms; R1 and R2 being such that the formation of the covalent bond between R1 and the target generates cleavage of the bond between R1 and R2 so as to free R2-M; and M is selected from the group consisting of a hydrogen atom and a pharmaceutically acceptable moiety. Alternatively, R1 and R2 can be inverted to form the formula II: B—R2-R1-M and being such that the formation of the covalent bond between R1 and the target generates cleavage of the bond between R1 and R2 so as to free R2-B.