(3RS,4R,5S,6S)-4,5-di-(4-methoxyphenylmethoxy)-3-hydroxy-7-(triphenylmethoxymethyl)octa-1,7-dien-6-yl 2,3,4-tri-O-(4-methoxyphenylmethyl)-6-O-triphenylmethyl-α-D-galactopyranoside | 1225450-76-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: (3RS,4R,5S,6S)-4,5-di-(4-methoxyphenylmethoxy)-3-hydroxy-7-(triphenylmethoxymethyl)octa-1,7-dien-6-yl 2,3,4-tri-O-(4-methoxyphenylmethyl)-6-O-triphenylmethyl-α-D-galactopyranoside
• CAS: 1225450-76-9
• 化学式: C₉₃H₉₄O₁₅
• 分子量: 1451.76
• InChiKey: TYLDBAOKIMDBNP-LYYJIMSDSA-N

反应信息

• 作为反应物：
  描述：

  (3RS,4R,5S,6S)-4,5-di-(4-methoxyphenylmethoxy)-3-hydroxy-7-(triphenylmethoxymethyl)octa-1,7-dien-6-yl 2,3,4-tri-O-(4-methoxyphenylmethyl)-6-O-triphenylmethyl-α-D-galactopyranoside 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 甲苯 为溶剂， 反应 0.17h， 以49%的产率得到2,3,4-O-tri-(4-methoxyphenylmethyl)-6-O-triphenylmethyl-α-D-galactopyranosyl-(1->4)-2,3-di-O-(4-methoxyphenylmethyl)-6-O-triphenylmethyl-α-Δ^5,5a-carba-D-galactopyranose
  参考文献：
  名称：

  Synthesis of a trigalacturonic acid analogue mimicking the expected transition state in the glycosidases

  摘要：

  A trigalacturonic acid analogue carrying a cyclohexene framework in place of the central pyranose ring was synthesized as a molecular probe for the mechanistic investigation of endo-polygalacturonase 1 (endo-PG 1). Preliminary enzymatic studies revealed that this analogue inhibited endo-PG 1 activity by about 30% at 0.3 mM concentration. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2009.12.024