8-methoxy-2,2,7,7,9,9-hexamethyl-3-oxiranylmethyl-1-oxa-3,8-diaza-spiro[4.5]decan-4-one | 1257558-44-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂螺癸烷衍生物
• 英文名称: 8-methoxy-2,2,7,7,9,9-hexamethyl-3-oxiranylmethyl-1-oxa-3,8-diaza-spiro[4.5]decan-4-one
• 英文别名: 8-methoxy-2,2,7,7,9,9-hexamethyl-3-(oxiran-2-ylmethyl)-1-oxa-3,8-diazaspiro[4.5]decan-4-one
• CAS: 1257558-44-3
• 化学式: C₁₇H₃₀N₂O₄
• 分子量: 326.436
• InChiKey: VRGPKGPZCNDXHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  54.5
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  1-methoxy-4-cyano-4-hydroxy-2,2,6,6-tetramethyl-piperidine 、 丙酮 、 硫酸 、 碳酸氢钠 、 溶剂黄146 在 乙酸乙酯 、 水 、 Sodium sulfate-III 作用下， 反应 18.0h， 以to leave 0.71 g of a tan residue的产率得到8-methoxy-2,2,7,7,9,9-hexamethyl-3-oxiranylmethyl-1-oxa-3,8-diaza-spiro[4.5]decan-4-one
  参考文献：
  名称：

  Sterically hindered amine light stabilizers

  摘要：

  本公开涉及具有氮原子低碱性和高热稳定性的立体位阻胺类光稳定剂（HALS）。它们的特点是在四甲基哌啶环的4位进行螺环取代（Spiro-NOR-HALS）。这些化合物在稳定聚合物，特别是热塑性聚烯烃，抵御氧化，热和光辐射的有害影响方面非常有用。这些化合物还可用于稳定酸催化和环境固化的涂层系统。当需要高加工温度时，它们尤其有用。

  公开号：

  US09045480B2

文献信息

• [EN] STERICALLY HINDERED AMINE STABILIZERS<br/>[FR] STABILISANTS D'AMINES À ENCOMBREMENT STÉRIQUE
  申请人：BASF SE

  公开号：WO2010142572A1

  公开（公告）日：2010-12-16

  The instant invention pertains to hindered amine compounds having at least two nitrogen atoms with different basicity. One part is substituted on the N-atom by alkoxy moieties and the other part is substituted on the N-atom by a hydroxy-alkyl moiety. These materials are particularly effective in stabilizing polymers, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation. The compounds are also particularly effective in stabilizing acid catalyzed and ambient cured coatings systems.

  这项瞬时发明涉及具有至少两个氮原子且碱度不同的受阻胺化合物。其中一部分在N原子上被烷氧基团取代，另一部分在N原子上被一个羟基-烷基基团取代。这些材料在稳定聚合物方面特别有效，尤其是热塑性聚烯烃，可以抵御氧化、热和光辐射的有害影响。这些化合物在稳定酸催化和环境固化的涂层系统方面也特别有效。
• [EN] NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS<br/>[FR] NOUVEAUX PHOTOSTABILISANTS D'AMINE À ENCOMBREMENT STÉRIQUE
  申请人：BASF SE

  公开号：WO2010142576A1

  公开（公告）日：2010-12-16

  The instant invention pertains to sterically hjndered amine Nght stabilizers (HALS) with low basicity at the nitrogen atom and high thermal stability. They are characterized by their spiro- substitution in the 4-position of the tetramethylpiperidine ring (Spiro-NOR-HALS). These compounds are particularly effective in stabilizing polymers, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation. The compounds are also particularly effective in stabilizing acid catalyzed and ambient cured coatings systems. They are particularly useful when high processing temperatures are additional required.

  本发明涉及具有氮原子低碱性和高热稳定性的立体位阻胺Nght稳定剂（HALS）。它们的特点是在四甲基哌啶环的4位进行螺-取代（Spiro-NOR-HALS）。这些化合物在稳定聚合物，特别是热塑性聚烯烃，抵御氧化、热和光辐射的有害影响方面特别有效。这些化合物在稳定酸催化和环境固化涂层系统方面也特别有效。当需要高加工温度时，它们尤其有用。
• STERICALLY HINDERED AMINE STABILIZERS
  申请人：Schoening Kai-Uwe

  公开号：US20120083557A1

  公开（公告）日：2012-04-05

  The instant invention pertains to hindered amine compounds having at least two nitrogen atoms with different basicity. One part is substituted on the N-atom by alkoxy moieties and the other part is substituted on the N-atom by a hydroxy-alkyl moiety. These materials are particularly effective in stabilizing polymers, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation. The compounds are also particularly effective in stabilizing acid catalyzed and ambient cured coatings systems.

  本发明涉及具有至少两个具有不同碱性的氮原子的受阻胺化合物。其中一部分在N原子上被烷氧基团取代，另一部分在N原子上被羟基烷基团取代。这些材料在稳定聚合物，特别是热塑性聚烯烃，抵抗氧化、热和光辐射的有害影响方面特别有效。这些化合物也特别有效地稳定酸催化和室温固化的涂层系统。
• NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS
  申请人：Schöning Kai-Uwe

  公开号：US20120108709A1

  公开（公告）日：2012-05-03

  The instant invention pertains to sterically hindered amine Night stabilizers (HALS) with low basicity at the nitrogen atom and high thermal stability. They are characterized by their spiro- substitution in the 4-position of the tetramethylpiperidine dine ring (Spiro-NOR-HALS). These compounds are particularly effective in stabilizing polymers, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation. The compounds are also particularly effective in stabilizing acid catalyzed and ambient cured coatings systems. They are particularly useful when high processing temperatures are additional required.

  本发明涉及具有低氮原子碱性和高热稳定性的立体位阻胺夜间稳定剂（HALS）。它们的特点是在四甲基哌啶环的4位进行螺环取代（Spiro-NOR-HALS）。这些化合物在稳定聚合物，特别是热塑性聚烯烃，抵抗氧化，热和光辐射的有害影响方面特别有效。这些化合物在稳定酸催化和环境固化的涂层系统方面也特别有效。当需要高加工温度时，它们特别有用。
• US9045480B2
  申请人：——

  公开号：US9045480B2

  公开（公告）日：2015-06-02