(4-methyl-benzyl)-trityl ether | 39834-48-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: (4-methyl-benzyl)-trityl ether
• 英文别名: (4-Methyl-benzyl)-trityl-aether；Trityl-p-methylbenzylaether；p-Methyl-benzyl-tritylether；1-Methyl-4-(trityloxymethyl)benzene
• CAS: 39834-48-5
• 化学式: C₂₇H₂₄O
• 分子量: 364.487
• InChiKey: SLFQXXPGECSOOW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.6
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (4-methyl-benzyl)-trityl ether 在 nanoporous MCM-41-SO₃H 作用下， 以 乙腈 为溶剂， 反应 0.17h， 以100%的产率得到(4-甲基苯基)甲醇
  参考文献：
  名称：

  Highly efficient protection of alcohols as trityl ethers under solvent-free conditions, and recovery catalyzed by reusable nanoporous MCM-41-SO3H

  摘要：

  简历摘要 一种高效的方法被开发出来，用于在室温下使用无溶剂球磨法，通过纳米孔道MCM-41-SO3H作为非均相催化剂，在三苯甲醇存在下保护醇为三苯甲醚。这种新的无溶剂和环保方法的优点包括低催化剂负载量、高效率和可重复使用性。所生成的三苯甲醚的去保护过程同样在该催化剂作用下于湿乙腈中高效完成。

  DOI：

  10.1016/j.crci.2014.01.003
• 作为产物：
  描述：

  对氯甲苯 在 lithium aluminium tetrahydride 、 乙醚 、 三乙胺 、 苯 作用下， 生成 (4-methyl-benzyl)-trityl ether
  参考文献：
  名称：

  The Relative Sensitivity of Triphenylmethyl Chloride to Electrophiles and Nucleophiles in Benzene Solution

  摘要：

  DOI：

  10.1021/ja01642a025

文献信息

• Fe(III)-catalyzed trityl benzyl ether formation and disproportionation cascade reactions to yield benzaldehydes
  作者：Xiaoyu Wang、Chuan Du、Hui Shi、Yadong Pang、Shengfei Jin、Yuqian Hou、Yanshi Wang、Xiaoshi Peng、Jianyong Xiao、Yang Liu、Yongxiang Liu、Maosheng Cheng

  DOI：10.1016/j.tet.2015.07.040

  日期：2015.9

  During investigating water-compatible Lewis acids catalyzed etherifications using alcohols as alkylating reagents directly, we developed Fe(III)-catalyzed trityl benzyl ether formations irradiated by microwave. Then an in situ trityl benzyl ether formation and disproportionation cascade reaction was achieved to yield the benzaldehyde products with good functional group tolerances under neat conditions

  在直接使用醇作为烷基化试剂研究与水相容的路易斯酸催化的醚化过程中，我们开发了Fe（III）催化的微波辐照的三苯甲基苄基醚形成。然后，在相对较高的温度下，在纯净条件下，实现了原位三苯甲基苄基醚的形成和歧化级联反应，从而得到具有良好官能团耐受性的苯甲醛产物。通过使用化学动力学图方法改变苄醇和三芳基甲醇上的取代基，探讨了底物对醚化和歧化的取代作用，并通过交叉实验研究了转化机理。醚化和歧化级联过程可以在实验室中方便地扩大规模，而不会损失很多效率。
• FeCl₃-Catalyzed Tritylation of Alcohols in Ionic Liquids
  作者：B. Sreedhar、P. Radhika、B. Neelima、D. V. D. B. Chowdary、M. V. Basaveswara Rao

  DOI：10.1080/00397910902838888

  日期：2009.10.12

  Abstract A simple and efficient protection of alcohols as trityl ethers is described using trityl chloride in the presence of 5 mol% FeCl3 as catalyst in ionic liquids at room temperature in shorter reaction times. This mild and efficient method gives access to the protection of a wide range of alcohols in good yields. The use of ionic liquid allows easy separation of the product and recycling of catalyst

  摘要 描述了在离子液体中在 5 mol% FeCl3 存在下使用三苯甲基氯作为催化剂，在室温下以较短的反应时间将醇类保护为三苯甲基醚的方法。这种温和而有效的方法可以以良好的收率保护各种醇。离子液体的使用使得产品的分离和催化剂的循环利用变得容易。
• NOVEL COMPOSITIONS AND USE THEREOF FOR MODIFICATION OF SUBSTRATE SURFACES
  申请人：AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L.

  公开号：US20170174931A1

  公开（公告）日：2017-06-22

  The present invention relates to non aqueous, graftable coating composition comprised of a homogenous solution of a polymer and a spin casting organic solvent, where the composition does not contain acidic compounds, coloring particles, pigments or dyes, and the polymer has a linear polymer chain structure which is comprised of repeat units derived from monomers containing a single polymerizable olefinic carbon double bond, and the polymer contains at least one triarylmethyl chalcogenide containing moiety which is selected from the group consisting of repeat units having structure (I) an end chain group unit of structure (II) and mixtures thereof, and the polymer does not contain any repeat units or end groups containing water ionizable groups, ionic groups, free thiol groups, or free hydroxy groups, and where A 1 , A 2 , and A 3 are independently an Aryl or a substituted Aryl; Y is a chalcogen selected from O, S, Se or Te; X 1 and X 2 are individually selected organic spacers; P 1 is an organic polymer repeat unit moiety derived from a monomer containing a single polymerizable olefinic carbon double bound, and P 2 is an end group moiety derived from a monomer containing a single polymerizable olefinic carbon double bound, and represents a direct valence bond to the linear polymer. The invention also relates to using this novel coating composition to form a grafted polymer film on a substrate.