P-n-propyl-P-(2,2,2-trifluoroethoxy)-N,N-bis(trimethylsilyl)aminophosphine | 476622-88-5

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: P-n-propyl-P-(2,2,2-trifluoroethoxy)-N,N-bis(trimethylsilyl)aminophosphine
• 英文别名: 1-[[Bis(trimethylsilyl)amino]-(2,2,2-trifluoroethoxy)phosphanyl]propane
• CAS: 476622-88-5
• 化学式: C₁₁H₂₇F₃NOPSi₂
• 分子量: 333.481
• InChiKey: BFVDWLANEIZRCO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.26
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  P-n-propyl-P-(2,2,2-trifluoroethoxy)-N,N-bis(trimethylsilyl)aminophosphine 在 溴 作用下， 以 甲苯 为溶剂， 反应 1.5h， 生成 [Bromo-propyl-(2,2,2-trifluoroethoxy)phosphaniumyl]-trimethylsilylazanide
  参考文献：
  名称：

  Synthesis and Characterization of Mixed-Substituent P- n -Propyl-N-trimethylsilylphosphoranimines

  摘要：

  One approach to the synthesis of polyphosphazenes is the condensation polymerization of phosphoranimines. In this work, several novel P-n-propyl-N-trimethylsilylphosphoranimines have been synthesized and characterized. Modifications to the literature synthetic routes were required to obtain the precursor phosphines. The N-trimethylsilylphosphoranimines were obtained though oxidation of the phosphine with bromine and then subsequent nucleophilic displacement using lithium phenoxide. These phosphoranimines were stable for long periods of time under dry inert conditions. NMR analyses revealed complex splitting patterns beyond typical coupling due to the stereocenter at phosphorus. We report several approaches to the n-propyl containing phosphines and phosphoranimines.

  DOI：

  10.1080/10426500307867
• 作为产物：
  描述：

  bis(trimethylsilyl)aminodichlorophosphine 以 乙醚 为溶剂， 生成 P-n-propyl-P-(2,2,2-trifluoroethoxy)-N,N-bis(trimethylsilyl)aminophosphine
  参考文献：
  名称：

  Synthesis and Characterization of Mixed-Substituent P- n -Propyl-N-trimethylsilylphosphoranimines

  摘要：

  One approach to the synthesis of polyphosphazenes is the condensation polymerization of phosphoranimines. In this work, several novel P-n-propyl-N-trimethylsilylphosphoranimines have been synthesized and characterized. Modifications to the literature synthetic routes were required to obtain the precursor phosphines. The N-trimethylsilylphosphoranimines were obtained though oxidation of the phosphine with bromine and then subsequent nucleophilic displacement using lithium phenoxide. These phosphoranimines were stable for long periods of time under dry inert conditions. NMR analyses revealed complex splitting patterns beyond typical coupling due to the stereocenter at phosphorus. We report several approaches to the n-propyl containing phosphines and phosphoranimines.

  DOI：

  10.1080/10426500307867

文献信息

• Synthesis and Characterization of Mixed-Substituent P- n -Propyl-N-trimethylsilylphosphoranimines
  作者：John R. Klaehn、Thomas A. Luther、Mason K. Harrup、Frederick F. Stewart

  DOI：10.1080/10426500307867

  日期：2003.7

  One approach to the synthesis of polyphosphazenes is the condensation polymerization of phosphoranimines. In this work, several novel P-n-propyl-N-trimethylsilylphosphoranimines have been synthesized and characterized. Modifications to the literature synthetic routes were required to obtain the precursor phosphines. The N-trimethylsilylphosphoranimines were obtained though oxidation of the phosphine with bromine and then subsequent nucleophilic displacement using lithium phenoxide. These phosphoranimines were stable for long periods of time under dry inert conditions. NMR analyses revealed complex splitting patterns beyond typical coupling due to the stereocenter at phosphorus. We report several approaches to the n-propyl containing phosphines and phosphoranimines.