luotonin D

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 吲哚萘啶生物碱
• 英文名称: luotonin D
• 英文别名: 3-Ethyl-13-methoxy-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one；3-ethyl-13-methoxy-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one
• 化学式: C₁₇H₁₄N₂O₂
• 分子量: 278.31
• InChiKey: KWPHZZGQGNWFCD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  44.1
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  harmine 在 selenium(IV) oxide 、 三乙胺 作用下， 以 乙醇 为溶剂， 反应 2.0h， 生成 luotonin D
  参考文献：
  名称：

  Alkaloids and phenylpropanoids from Peganum nigellastrum

  摘要：

  Two canthin-6-one alkaloids, luotonins C and D, and two phenylpropanoids. dihydrosinapyl ferulate and dihydroconiferyl ferulate, were isolated from the aerial parts of Peganum nigellastrum along with four known alkaloids, harmine, 3-phenylquinoline, 3-(4-hydroxyphenyl)quinoline and 3-(1H-indol-3-yl)quinoline. Their structures were elucidated by spectroscopic techniques. The structures of luotonins C and D were also confirmed by chemical synthesis. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(99)00440-9

文献信息

• Alkaloids and phenylpropanoids from Peganum nigellastrum
  作者：Zhong-Ze Ma、Yoshio Hano、Taro Nomura、Ying-Jie Chen

  DOI：10.1016/s0031-9422(99)00440-9

  日期：2000.4

  Two canthin-6-one alkaloids, luotonins C and D, and two phenylpropanoids. dihydrosinapyl ferulate and dihydroconiferyl ferulate, were isolated from the aerial parts of Peganum nigellastrum along with four known alkaloids, harmine, 3-phenylquinoline, 3-(4-hydroxyphenyl)quinoline and 3-(1H-indol-3-yl)quinoline. Their structures were elucidated by spectroscopic techniques. The structures of luotonins C and D were also confirmed by chemical synthesis. (C) 2000 Elsevier Science Ltd. All rights reserved.