Brilliantgruen | 630-98-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: Brilliantgruen
• 英文别名: brilliant green；Triphenylcarbinol, 4,4'-bisdiethylamino-；bis[4-(diethylamino)phenyl]-phenylmethanol
• CAS: 630-98-8
• 化学式: C₂₇H₃₄N₂O
• 分子量: 402.58
• InChiKey: FIFUHAFCHMUQIM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  30
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  26.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  Brilliantgruen 在 盐酸 、 zinc(II) chloride 作用下， 生成 碱性绿 1
  参考文献：
  名称：

  Doebner, Justus Liebigs Annalen der Chemie, 1883, vol. 217, p. 248

  摘要：

  DOI：
• 作为产物：
  描述：

  碱性绿 1 在 hydroxide 作用下， 以 水 为溶剂， 生成 Brilliantgruen
  参考文献：
  名称：

  Gupta, Susanta K. Sen; Arvind, Udai, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1994, vol. 33, # 10, p. 998 - 1000

  摘要：

  DOI：

文献信息

• PHOTOREACTIVE SYNTHETIC REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF
  申请人：The Regents of the University of California

  公开号：US20150158811A1

  公开（公告）日：2015-06-11

  The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.

  本公开提供了一种光反应合成蛋白功能调节剂。本公开还提供了一种包括所述合成调节剂的光调控多肽。还提供了包括所述光调控多肽的细胞和膜。本公开还提供了一种调节蛋白功能的方法，涉及使用光。
• Kinetics of Fading of Some Triphenylmethane Dyes: Effects of Electric Charge, Substituent, and Aqueous Binary Mixtures of Dimethyl Sulfoxide and 2-Propanol
  作者：B. Samiey、Z. Dalvand

  DOI：10.1002/kin.20831

  日期：2014.1

  The rate constants of alkaline fading of a number of triphenylmethane (TPM) dyes including methyl green (ME2+), brilliant green (BG+), fuchsin acid (FA2−), and bromophenol blue (BPB2−) were obtained in aqueous binary mixtures of 2‐propanol (protic solvent) and dimethyl sulfoxide (DMSO) (aprotic solvent) at different temperatures. It was observed that the reaction rate constants of BG+ and ME2+ increased

  获得了包括甲基绿（ME 2+），亮绿色（BG +），品红酸（FA 2−）和溴酚蓝（BPB 2-）在内的许多三苯甲烷（TPM）染料的碱性褪色速率常数。2-丙醇（质子溶剂）和二甲基亚砜（DMSO）（非质子溶剂）在不同温度下的二元水性混合物。观察到BG +和ME 2+的反应速率常数增加，FA 2−和BPB 2−的反应速率常数增加随着2-丙醇水溶液和DMSO二元混合物重量百分比的增加而降低。2-丙醇和DMSO除与TPM染料发生疏水相互作用外，还分别通过氢键和离子-偶极相互作用与所用的TPM分子相互作用。通过SESMORTAC模型获得了这些溶液中褪色反应的基本速率常数。此外，研究了许多TPM染料的电荷和取代基对其碱性褪色速率的影响。
• Equilibrium and Kinetic Studies on the Formation of Triphenylmethanols from Triphenylmethane Dyes
  作者：Takuyuki Hagiwara、Shoji Motomizu

  DOI：10.1246/bcsj.67.390

  日期：1994.2

  triphenylmethane dyes, the rate constants of hydration and dehydration reactions, and equilibrium constants in an aqueous solution were measured by a stopped-flow method. An increase in the number of dialkylamino groups caused a decrease in the rates and the equilibrium constants of the hydration, and the more the electron-donating effect of the dialkylamino groups, the slower the hydration rate became. The more

  对五种三苯甲烷染料，采用停流法测定了水合和脱水反应的速率常数和在水溶液中的平衡常数。二烷基氨基数目的增加导致水合速率和平衡常数的降低，并且二烷基氨基的给电子效应越大，水合速率变得越慢。质子化程度更高的醌类化合物很容易转化为相应的醇类。根据平衡常数，孔雀石绿被确定是五种染料中在水性介质中与杂多酸离子缔合的最佳试剂。
• PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF
  申请人：Trauner Dirk

  公开号：US20090181454A1

  公开（公告）日：2009-07-16

  The present invention provides a synthetic regulator of glutamate receptor function, which regulator is a light-sensitive (photoreactive) regulator. The present invention further provides a light-regulated glutamate receptor that includes a subject synthetic regulator non-covalently associated with the glutamate receptor. Also provided are cells and membranes comprising a subject light-regulated glutamate receptor. The present invention further provides methods of modulating glutamate receptor function, involving use of light. The present invention further provides methods of identifying agents that modulate glutamate receptor function.

  本发明提供了一种合成的谷氨酸受体功能调节剂，该调节剂是一种光敏感（光反应性）调节剂。本发明还提供了一种光调节的谷氨酸受体，其中包括与谷氨酸受体非共价结合的主体合成调节剂。还提供了包括主体光调节谷氨酸受体的细胞和膜。本发明还提供了使用光调节谷氨酸受体的调节谷氨酸受体功能的方法。本发明还提供了识别调节谷氨酸受体功能的药剂的方法。
• Photoreactive Synthetic Regulator of Protein Function and Methods of Use Thereof
  申请人：Trauner Dirk

  公开号：US20110207213A1

  公开（公告）日：2011-08-25

  The present disclosure provides a photoreactive synthetic regulator of protein function. The present disclosure further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present disclosure further provides methods of modulating protein function, involving use of light.

  本公开提供了一种光敏合成蛋白功能调节剂。本公开进一步提供了一种包含所述合成调节剂的光调控多肽。同时还提供了包含所述光调控多肽的细胞和膜。本公开进一步提供了利用光调节蛋白功能的方法。