1,1,1,3-tetramethyl-3-methoxy-3-(3-aminopropyl)disiloxane | 1616272-43-5

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 1,1,1,3-tetramethyl-3-methoxy-3-(3-aminopropyl)disiloxane
• 英文别名: 1,1,1,3-Tetramethyl-3-methoxy-3-(3-amino-propyl)disiloxane；3-(methoxy-methyl-trimethylsilyloxysilyl)propan-1-amine
• CAS: 1616272-43-5
• 化学式: C₈H₂₃NO₂Si₂
• 分子量: 221.447
• InChiKey: NSCUMUSBWVNYSP-UHFFFAOYSA-N

物化性质

• 熔点：
  88-89 °C
• 沸点：
  180.9±23.0 °C(predicted)
• 密度：
  0.891±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.91
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,1,1,3-tetramethyl-3-methoxy-3-(3-aminopropyl)disiloxane 、 六甲基二硅氮烷 在 氯化铵 作用下， 反应 24.0h， 以70.7%的产率得到1-(trimethylsilyl)-2-methyl-2-trimethylsiloxy-1-aza-2-silacyclopentane
  参考文献：
  名称：

  Silylated derivatives of azasilacyclopentanes

  摘要：

  Catalytic intramolecular cyclization of 3-aminopropylalkoxysilanes and 3-aminopropylalkoxydisiloxanes in the presence of hexamethyldisilazane has been studied; structure and reactivity of the formed azasilacyclopentanes have been investigated. In particular, the prepared cyclic azasilanes were studied by H-1, Si-29, and C-13 NMR spectroscopy. Possibility of catalytic co-condensation of the compounds containing methoxy and trimethylsiloxy groups with preservation of azasilacyclopentane structure has been demonstrated. Depending on temperature and the reactants ratio, the interaction of 3-aminopropylmethyldimethoxysilane with hexamethyldisilazane can yield 1-(trimethylsilyl)-2-methyl-2-methoxy-1-aza-2-silacyclopentane or the polymer bearing azasilacyclopentane fragments in the main chain.

  DOI：

  10.1134/s1070363214050168
• 作为产物：
  描述：

  三甲基硅醇 、 3-氨丙基二甲氧基甲基硅烷 反应 3.0h， 以85.6%的产率得到1,1,1,3-tetramethyl-3-methoxy-3-(3-aminopropyl)disiloxane
  参考文献：
  名称：

  Silylated derivatives of azasilacyclopentanes

  摘要：

  Catalytic intramolecular cyclization of 3-aminopropylalkoxysilanes and 3-aminopropylalkoxydisiloxanes in the presence of hexamethyldisilazane has been studied; structure and reactivity of the formed azasilacyclopentanes have been investigated. In particular, the prepared cyclic azasilanes were studied by H-1, Si-29, and C-13 NMR spectroscopy. Possibility of catalytic co-condensation of the compounds containing methoxy and trimethylsiloxy groups with preservation of azasilacyclopentane structure has been demonstrated. Depending on temperature and the reactants ratio, the interaction of 3-aminopropylmethyldimethoxysilane with hexamethyldisilazane can yield 1-(trimethylsilyl)-2-methyl-2-methoxy-1-aza-2-silacyclopentane or the polymer bearing azasilacyclopentane fragments in the main chain.

  DOI：

  10.1134/s1070363214050168

文献信息

• Silylated derivatives of azasilacyclopentanes
  作者：T. R. Salikhov、V. M. Kopylov、D. I. Shragin

  DOI：10.1134/s1070363214050168

  日期：2014.5

  Catalytic intramolecular cyclization of 3-aminopropylalkoxysilanes and 3-aminopropylalkoxydisiloxanes in the presence of hexamethyldisilazane has been studied; structure and reactivity of the formed azasilacyclopentanes have been investigated. In particular, the prepared cyclic azasilanes were studied by H-1, Si-29, and C-13 NMR spectroscopy. Possibility of catalytic co-condensation of the compounds containing methoxy and trimethylsiloxy groups with preservation of azasilacyclopentane structure has been demonstrated. Depending on temperature and the reactants ratio, the interaction of 3-aminopropylmethyldimethoxysilane with hexamethyldisilazane can yield 1-(trimethylsilyl)-2-methyl-2-methoxy-1-aza-2-silacyclopentane or the polymer bearing azasilacyclopentane fragments in the main chain.