代谢
锶-90的放射性允许它在吸入、摄入或皮肤接触后渗透进人体。锶-90表现出与钙类似的生物化学行为。进入生物体后,大约70-80%的剂量会被排出体外。几乎所有的剩余锶-90都会沉积在骨骼和骨髓中,剩余的1%留在血液和软组织中。锶的新陈代谢包括与蛋白质的结合相互作用,以及基于其与钙的相似性,可能与各种无机阴离子如碳酸根和磷酸根,以及羧酸如柠檬酸盐和乳酸盐形成复合物。锶-90主要通过尿液和粪便排出体外。
The radioactivity of strontium-90 allow it to penetrate the body following inhalation, ingestion, or dermal exposure. Strontium-90 exhibits biochemical behavior similar to calcium. After entering the organism, about 70-80% of the dose is excreted. Virtually all remaining strontium-90 is deposited in bones and bone marrow, with the remaining 1% remaining in blood and soft tissues. The metabolism of strontium consists of binding interactions with proteins and, based on its similarity to calcium, probably complex formation with various inorganic anions such as carbonate and phosphate, and carboxylic acids such as citrate and lactate. Strontium-90 is eliminated mainly in the urine and faeces. (L1135)
来源:Toxin and Toxin Target Database (T3DB)