8-Ethylpyrazolo[1,5-a][1,3,5]triazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡唑并三嗪类
• 英文名称: 8-Ethylpyrazolo[1,5-a][1,3,5]triazine
• 英文别名: 8-ethylpyrazolo[1,5-a][1,3,5]triazine
• 化学式: C₇H₈N₄
• 分子量: 148.17
• InChiKey: TZIZNQGUBRJGJM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  43.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE
  申请人：TAKEDA PHARMACEUTICAL COMPANY LIMITED

  公开号：US20210106607A1

  公开（公告）日：2021-04-15

  The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.
• [EN] PROTEIN KINASE INHIBITORS<br/>[FR] INHIBITEURS DE PROTÉINES KINASES
  申请人：ASTAR BIOTECH LLC

  公开号：WO2014019338A1

  公开（公告）日：2014-02-06

  Disclosed are compounds of Formula I, as well as pharmaceutically acceptable salts, hydrates, isomers, or solvates thereof. Also disclosed are pharmaceutical compositions which comprise the compounds of Formula I, and methods for inhibiting protein kinase and methods of treating diseases, such as cancers, inflammation.
• [EN] PROTEIN KINASE INHIBITORS<br/>[FR] INHIBITEURS DE PROTÉINE KINASE
  申请人：ASTAR BIOTECH LLC

  公开号：WO2016029776A1

  公开（公告）日：2016-03-03

  The compounds of Formula (VIII) with absolute configuration R or S, as well as pharmaceutically acceptable salts, hydrates, or solvates thereof, wherein the variables are described herein. The pharmaceutical compositions which comprise the compounds of Formula (VIII), and methods for inhibiting protein kinase and methods of treating diseases, such as cancers, inflammation are provided.