2-Chloro-4-ethenyl-1,3,5-triazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 2-Chloro-4-ethenyl-1,3,5-triazine
• 英文别名: 2-chloro-4-ethenyl-1,3,5-triazine
• 化学式: C₅H₄ClN₃
• 分子量: 141.56
• InChiKey: PIYRQQFFOYZHAV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] NOVEL HETEROARYL AND HETEROCYCLE COMPOUNDS, COMPOSITIONS AND METHODS<br/>[FR] NOUVEAUX COMPOSÉS HÉTÉROARYLIQUES ET HÉTÉROCYCLIQUES ET COMPOSITIONS ET PROCÉDÉS S'Y RAPPORTANT
  申请人：HUTCHISON MEDIPHARMA LTD

  公开号：WO2014015523A1

  公开（公告）日：2014-01-30

  The invention relates to novel heteroaryl and heterocycle compounds and pharmaceutical compositions comprising them, uses and methods thereof for inhibiting the activity of PI3k and for treating inflammatory and autoimmune disorders diseases and cancer.

  这项发明涉及新颖的杂环芳基和杂环化合物，以及包括它们的药物组合物，用途和方法，用于抑制PI3k的活性，并用于治疗炎症性和自身免疫性疾病以及癌症。
• [EN] NOVEL COMPOUNDS AS BTK INHIBITORS<br/>[FR] NOUVEAUX COMPOSÉS UTILISÉS COMME INHIBITEURS DE BTK
  申请人：SUN PHARMA ADVANCED RES CO LTD

  公开号：WO2017168454A2

  公开（公告）日：2017-10-05

  The present invention relates to novel compounds of Formula I as Bruton tyrosine kinase inhibitors, process of preparation thereof, and to the use of the compounds in the preparation 5 of pharmaceutical compositions for the therapeutic treatment of disorders involving mediation of Bruton tyrosine kinase in humans.
• [EN] NOVEL HYDRAZINO COMPOUNDS AS BTK INHIBITORS<br/>[FR] NOUVEAUX COMPOSÉS HYDRAZINO UTILISÉS COMME INHIBITEURS DE BTK
  申请人：SUN PHARMA ADVANCED RES CO LTD

  公开号：WO2017134685A2

  公开（公告）日：2017-08-10

  The present invention relates to novel hydrazino compounds of Formula (I) as Bruton tyrosine kinase inhibitors, process of preparation thereof, and to the use of the compounds in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders involving mediation of Bruton tyrosine kinase in humans.