5-(6-Chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-4-ene | 200432-88-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吖庚因类
• 英文名称: 5-(6-Chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-4-ene
• 英文别名: 2-(6-chloropyridin-3-yl)-9-azabicyclo[4.2.1]non-2-ene
• CAS: 200432-88-8
• 化学式: C₁₃H₁₅ClN₂
• 分子量: 234.72
• InChiKey: TVSNVPGPFGAKPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  24.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] 9-AZABICYCLO[4.2.1]NON-2-ENE DERIVATIVES AS LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTORS<br/>[FR] DERIVES DE 9-AZABICYCLO[4.2.1]NONE-2-ENE EN TANT QUE LIGANDS POUR RECEPTEURS NICOTINIQUES D'ACETYLCHOLINE
  申请人：UNIV BRISTOL

  公开号：WO2001049690A1

  公开（公告）日：2001-07-12

  9-Azabicyclo[4.2.1]non-2-ene derivatives, which are ligands for nicotinic acetylcholine receptors (nAChRs), are disclosed. The compounds show a capacity to differentiate between different subtypes of nAChRs. Pharmaceutical compositions containing such compounds and a method of using such compounds in the treatment of a disease or disorder which is responsive to the activity of nAChR modulators are also disclosed.